PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Ck-beta-11 4 Target Target Exodus-2 27 1 0.10 -0.85 0.25 0.84
Epidermal Growth Factor Receptor 24,772 Target Target Epiregulin 291 80 0.03 -0.85 0.27 0.69
CXCL10/IP-10 114 Target Target CXCL11 526 27 0.11 -0.85 0.24 0.82
ELC 355 Target Target Exodus-2 27 7 0.07 -0.85 0.26 0.79
ADSF 11 Target Target Adiponectin 11,994 3 0.01 -0.85 0.27 0.66
CD22 1,591 Target Disease Leukemia 162,805 430 0.03 -0.85 0.27 0.65
Dihydropteroate Synthase 408 Target Disease Malaria 56,215 110 0.02 -0.85 0.27 0.67
CCL2 3,560 Target Target CXCL3 145 38 0.05 -0.85 0.26 0.75
CA125 Antigen 78 Target Disease Carcinoma 433,099 21 0.00 -0.85 0.27 0.59
Lanosterol 14 Alpha-Demethylase 101 Target Disease Cholesterol 182,390 27 0.01 -0.86 0.27 0.61
CD4 112,219 Target Target 4-1BB Ligand 135 36 0.01 -0.86 0.27 0.63
CD146 729 Target Target CD34 24,598 190 0.04 -0.86 0.26 0.71
BMP-7 1,112 Target Target BMP-4 1,255 169 0.14 -0.86 0.15 0.85
Exodus-2 27 Target Target CCL21 808 7 0.05 -0.86 0.26 0.76
ACRP30 102 Target Disease Diabetes 332,602 27 0.00 -0.86 0.26 0.59
Mu Opioid Receptor 4,576 Target Target Mu-Type Opioid Receptor 19 5 0.02 -0.86 0.26 0.69
AMAC-1 19 Target Disease Inflammation 252,734 5 0.00 -0.86 0.26 0.59
Eotaxin-2/CCL24 19 Target Disease Inflammation 252,734 5 0.00 -0.86 0.26 0.59
DDR2 194 Target Disease Cancer 1,053,491 51 0.00 -0.86 0.26 0.57
CCL2 3,560 Target Target CCL1 220 55 0.06 -0.86 0.25 0.76
Calmodulin 25,240 Target Target DAPK2 27 7 0.01 -0.86 0.26 0.65
Epidermal Growth Factor Receptor 24,772 Target Target ERBB3 1,154 289 0.05 -0.86 0.25 0.72
CCL3 1,427 Target Disease Inflammation 252,734 365 0.02 -0.86 0.26 0.63
Maternal Embryonic Leucine Zipper Kinase 39 Target Disease Glioblastoma 17,933 10 0.01 -0.86 0.26 0.66
Kappa-Type Opioid Receptor 4 Target Target Sphingosine 1-Phosphate Receptor 1 150 1 0.04 -0.86 0.25 0.77
Tissue-Type Plasminogen Activator 5,020 Target Target Urokinase-Type Plasminogen Activator 3,939 603 0.14 -0.86 0.15 0.83
Myeloperoxidase 16,181 Target Disease Inflammation 252,734 3,923 0.06 -0.86 0.24 0.68
CD4 112,219 Target Target CD137 474 120 0.02 -0.86 0.25 0.64
CXCL9 1,016 Target Disease Inflammation 252,734 256 0.02 -0.86 0.25 0.63
CCL5 2,002 Target Target CXCL9 1,016 180 0.13 -0.87 0.18 0.83
Estrogen Receptor Beta 1,924 Target Target Egl Nine Homolog 1 4 1 0.01 -0.87 0.25 0.69
EPHB3 118 Target Target EPHB1 137 17 0.13 -0.87 0.14 0.87
CCL4 5,638 Target Target CCBL1 4 1 0.01 -0.87 0.25 0.66
Xaa-Pro Dipeptidase 4 Target Disease Diabetic Nephropathy 12,496 1 0.00 -0.87 0.25 0.64
Antithrombin 13,773 Target Drug Alprostadil Injection (Caverject)- FDA 4 1 0.00 -0.87 0.25 0.64
Ck-beta-11 4 Target Target CD34 24,598 1 0.00 -0.87 0.25 0.63
Epidermal Growth Factor Receptor 24,772 Target Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.63
Xaa-Pro Dipeptidase 4 Target Target EGF 27,487 1 0.00 -0.87 0.25 0.62
Glutathione S-Transferase Mu 2 8 Target Disease Inflammation 252,734 2 0.00 -0.87 0.25 0.58
Prostaglandin Reductase 1 8 Target Disease Inflammation 252,734 2 0.00 -0.87 0.25 0.58
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 Target Target Collagen 138,882 1 0.00 -0.87 0.25 0.59
Ck-beta-11 4 Target Disease Breast Cancer 173,695 1 0.00 -0.87 0.25 0.59
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 Target Disease Inflammation 252,734 1 0.00 -0.87 0.25 0.58
ADRBK2 8 Target Disease Cancer 1,053,491 2 0.00 -0.87 0.25 0.55
CD62L/L-Selectin 8 Target Disease Cancer 1,053,491 2 0.00 -0.87 0.25 0.55
CCL3 1,427 Target Target CXCL10 2,386 238 0.13 -0.87 0.17 0.83
CCL5 2,002 Target Target CXCL10/IP-10 114 27 0.06 -0.87 0.24 0.76
CXCL10 2,386 Target Disease Inflammation 252,734 585 0.02 -0.87 0.25 0.64
CCL5 2,002 Target Target CCL8 197 45 0.07 -0.87 0.23 0.78
DAPK2 27 Target Target DAPK1 205 6 0.08 -0.87 0.22 0.81
CCL7 274 Target Target CCL5 2,002 60 0.08 -0.87 0.22 0.79
3-Phosphoinositide-Dependent Protein Kinase 1 230 Target Disease Cancer 1,053,491 55 0.00 -0.87 0.24 0.57
CCL3 1,427 Target Target CXCL2 750 123 0.12 -0.87 0.16 0.83
Crth2 Receptor 51 Target Disease Inflammation 252,734 12 0.00 -0.87 0.24 0.59
CCL14 34 Target Disease Inflammation 252,734 8 0.00 -0.87 0.24 0.59
AMY2B 21 Target Target AMY1A 13 2 0.12 -0.87 0.15 0.87
APOA1 958 Target Target APOA2 118 25 0.07 -0.88 0.21 0.79
Aurora B kinase 415 Target Disease Cancer 1,053,491 96 0.00 -0.88 0.23 0.57
Antithrombin 13,773 Target Drug Angiomax (Bivalirudin)- FDA 13 3 0.01 -0.88 0.23 0.65
CCL2 3,560 Target Target CXCL9 1,016 190 0.10 -0.88 0.19 0.80
Bile Salt Export Pump 476 Target Target Multidrug Resistance-Associated Protein 2 462 57 0.12 -0.88 0.12 0.85
CXCL11 526 Target Disease Inflammation 252,734 119 0.01 -0.88 0.23 0.61
CD1A 2,739 Target Target CD68 6,424 458 0.11 -0.88 0.17 0.80
EGF 27,487 Target Target ERBB3 1,154 251 0.04 -0.88 0.22 0.71
CXCL9 1,016 Target Target CXCL4/PF4 9 2 0.02 -0.88 0.22 0.72
BAFF 1,240 Target Target CD254 9 2 0.02 -0.88 0.22 0.72
AMAC-1 19 Target Target CCL18 256 4 0.06 -0.88 0.21 0.79
CCL2 3,560 Target Target CXCL4/PF4 9 2 0.01 -0.88 0.22 0.68
Androgen Receptor 12,918 Target Drug Doxorubicin-Formaldehyde Conjugate 9 2 0.01 -0.88 0.22 0.65
CXCL10/IP-10 114 Target Disease Inflammation 252,734 25 0.00 -0.88 0.22 0.60
ACVR1B 23 Target Target Activin A 2,048 5 0.02 -0.88 0.22 0.72
ERBB4 994 Target Target EGF 27,487 210 0.04 -0.88 0.21 0.70
CXCL16 341 Target Disease Inflammation 252,734 74 0.01 -0.88 0.22 0.61
CA 72-4 184 Target Target CA 15-3 898 34 0.08 -0.89 0.18 0.80
CCL7 274 Target Target CCL3 1,427 51 0.08 -0.89 0.19 0.79
Cox-2 21,583 Target Disease Inflammation 252,734 4,343 0.06 -0.89 0.20 0.68
CCL3 1,427 Target Target CCL8 197 38 0.07 -0.89 0.19 0.78
Glutathione Transferase Omega-1 14 Target Disease Breast Cancer 173,695 3 0.00 -0.89 0.21 0.59
Endostatin 1,599 Target Target Collagen 138,882 339 0.02 -0.89 0.21 0.65
Eotaxin-2/CCL24 19 Target Disease Asthma 109,610 4 0.00 -0.89 0.21 0.60
Macrophage Metalloelastase 100 Target Disease Inflammation 252,734 21 0.00 -0.89 0.21 0.60
ApoE4 1,525 Target Disease Cholesterol 182,390 316 0.02 -0.89 0.21 0.64
Mu Opioid Receptor 4,576 Target Drug Dpdpe 1,204 206 0.09 -0.89 0.17 0.79
Cysteinyl Leukotriene Receptor 2 24 Target Disease Inflammation 252,734 5 0.00 -0.89 0.21 0.58
4-1BB Receptor 20 Target Target CD137 474 4 0.04 -0.89 0.20 0.76
Collagen 138,882 Target Target BMP-2 3,889 783 0.03 -0.89 0.20 0.66
CCL4 5,638 Target Target CCL5 2,002 316 0.09 -0.89 0.16 0.79
CD1A 2,739 Target Target CD14 9,941 456 0.09 -0.89 0.17 0.77
CD1A 2,739 Target Target CD4 112,219 547 0.03 -0.89 0.20 0.66
CCL7 274 Target Target CXCL10 2,386 51 0.06 -0.89 0.19 0.77
CNTF 1,613 Target Target BDNF 11,163 292 0.07 -0.89 0.18 0.75
Annexin A1 406 Target Disease Inflammation 252,734 82 0.01 -0.89 0.20 0.61
CD95 4,266 Target Target Apo I 55 11 0.02 -0.89 0.20 0.71
Epidermal Growth Factor Receptor 24,772 Target Disease Non Small Cell Lung Cancer 28,563 2,827 0.11 -0.89 0.11 0.78
CCL14 34 Target Target CCL8 197 6 0.07 -0.89 0.18 0.81
Toll-Like Receptor 2 2,174 Target Disease Inflammation 252,734 434 0.02 -0.89 0.20 0.63
CXCL7 76 Target Target CCL2 3,560 15 0.03 -0.89 0.20 0.72
Hiv-1 Integrase 1,199 Target Drug Kadsurarin 5 1 0.01 -0.89 0.20 0.70
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target Glutathione S-Transferase A3 15 3 0.01 -0.89 0.20 0.67
CCL5 2,002 Target Target Small Inducible Cytokine A2 5 1 0.01 -0.89 0.20 0.69