PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
CSF2/GM-CSF 2 Target Disease Inflammation 252,734 2 0.00 -0.58 1.00 0.60
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 Target Disease Leukemia 162,805 4 0.00 -0.45 1.00 0.62
Heat Shock Protein Hsp 90-Beta 3 Target Disease Shock 134,031 3 0.00 -0.50 1.00 0.62
EoCP-1 1 Target Disease Asthma 109,610 1 0.00 -0.71 1.00 0.61
Neutral Alpha-Glucosidase C 6 Target Target Alpha-Glucosidase 4,319 6 0.04 -0.38 1.00 0.72
CXCL10/IP-10 114 Target Target CXCL10 2,386 114 0.22 -0.09 1.00 0.82
Angiotensin Converting Enzyme 31,674 Target Target Angiotensin-Converting Enzyme 2 665 665 0.14 -0.04 1.00 0.76
Alpha-Amylase 7,171 Target Target Pancreatic Alpha-Amylase 423 423 0.24 -0.05 1.00 0.81
Collagenase-3 367 Target Target Collagenase 3 367 367 1.00 -0.00 1.00 1.00
Metabotropic Glutamate Receptor 1 221 Target Target Glutamate Receptor 1 352 221 0.79 -0.04 1.00 0.97
Alpha-Glucosidase 4,319 Target Target Lysosomal Alpha-Glucosidase 105 105 0.16 -0.10 1.00 0.79
Eotaxin 2,457 Target Target Eotaxin-3/CCL26 26 26 0.10 -0.19 1.00 0.77
Eotaxin 2,457 Target Target Eotaxin-2/CCL24 19 19 0.09 -0.22 1.00 0.76
CD4 112,219 Target Target CTLA-4/Fc 4 4 0.01 -0.45 1.00 0.62
Artemin 184 Target Target Enovin 3 3 0.13 -0.50 1.00 0.81
Alcohol Dehydrogenase 8,492 Target Drug Antizol (Fomepizole)- FDA 2 2 0.02 -0.58 1.00 0.68
Alpha-Glucosidase 4,319 Target Drug Alglucosidase Alfa (Lumizyme)- FDA 1 1 0.02 -0.71 1.00 0.69
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target C1orf41 1 1 0.01 -0.71 1.00 0.68
BNP 6,842 Target Target BNP/NPPB 1 1 0.01 -0.71 1.00 0.68
Myeloperoxidase 16,181 Target Drug Azithromycin (Zithromax Injection)- FDA 1 1 0.01 -0.71 1.00 0.66
CD4 112,219 Target Disease Infection Upper Respiratory Tract 1 1 0.00 -0.71 1.00 0.61
ApoE2 517 Target Target APOE 12,771 454 0.18 -0.34 0.88 0.78
Exodus-2 27 Target Target Exodus-3 8 7 0.48 -0.30 0.88 0.92
ACAT2 145 Target Disease Cholesterol 182,390 122 0.02 -0.40 0.84 0.65
D(1a) Dopamine Receptor 51 Target Target D(2) Dopamine Receptor 1,559 41 0.15 -0.44 0.80 0.80
CD4 112,219 Target Target CCL27/CTACK 5 4 0.01 -0.45 0.80 0.62
BAFF 1,240 Target Target BAFFR 44 33 0.14 -0.49 0.75 0.80
ELC 355 Target Target Ck-beta-11 4 3 0.08 -0.50 0.75 0.78
ApoE4 1,525 Target Target APOE 12,771 1,119 0.25 -0.49 0.73 0.82
Mu Opioid Receptor 4,576 Target Target Opioid Receptor Mu 71 51 0.09 -0.53 0.72 0.76
ACRP30 102 Target Target Adiponectin 11,994 72 0.07 -0.54 0.71 0.73
EGF 27,487 Target Target beta-Cellulin 17 12 0.02 -0.54 0.71 0.67
CXCL11 526 Target Target CXCL10 2,386 369 0.33 -0.50 0.70 0.87
Calmodulin 25,240 Target Target CAMK4 43 30 0.03 -0.55 0.70 0.69
CD14 9,941 Target Target Endotoxin receptor 115 80 0.07 -0.55 0.70 0.74
CA125 Antigen 78 Target Disease Cancer 1,053,491 54 0.01 -0.55 0.69 0.59
Alpha-Amylase 7,171 Target Target AMY1A 13 9 0.03 -0.55 0.69 0.70
Ns3 3,189 Target Disease Hepatitis 163,842 2,173 0.10 -0.56 0.68 0.71
ApoE2 517 Target Target ApoE4 1,525 348 0.39 -0.50 0.67 0.89
Xanthine Oxidase 8,860 Target Drug Anturane (Sulfinpyrazone)- FDA 3 2 0.01 -0.58 0.67 0.67
CXCL9 1,016 Target Target CXCL10 2,386 676 0.43 -0.49 0.67 0.90
APOE 12,771 Target Target APOC1 126 82 0.06 -0.59 0.65 0.73
ELC 355 Target Target Exodus-3 8 5 0.09 -0.61 0.62 0.79
CA 15-3 898 Target Disease Breast Cancer 173,695 557 0.04 -0.62 0.62 0.67
ATAC 239 Target Disease Cancer 1,053,491 148 0.01 -0.62 0.62 0.59
Erbb2 4,536 Target Target ERBB3 1,154 711 0.31 -0.57 0.62 0.86
Cathepsin G 1,613 Target Target Elastase 13,875 985 0.21 -0.60 0.61 0.81
APOA1 958 Target Disease Cholesterol 182,390 585 0.04 -0.62 0.61 0.67
ATAC 239 Target Disease Breast Cancer 173,695 144 0.02 -0.63 0.60 0.65
Adenosine Deaminase 6,613 Target Target ADAT1 5 3 0.02 -0.63 0.60 0.69
CCL7 274 Target Target CCL2 3,560 164 0.17 -0.62 0.60 0.81
CEA 17,022 Target Target CA 72-4 184 108 0.06 -0.64 0.59 0.72
DDR2 194 Target Target Collagen 138,882 113 0.02 -0.65 0.58 0.65
CA125 Antigen 78 Target Disease Ovarian Cancer 33,996 45 0.03 -0.65 0.58 0.68
AKT2 873 Target Target AKT3 293 164 0.32 -0.60 0.56 0.88
CXCL3 145 Target Target CXCL2 750 81 0.25 -0.63 0.56 0.86
CXCL9 1,016 Target Target CXCL11 526 293 0.40 -0.56 0.56 0.91
Epiregulin 291 Target Target EGF 27,487 162 0.06 -0.66 0.56 0.71
CXCL10 2,386 Target Target CXCL4/PF4 9 5 0.03 -0.67 0.56 0.72
CD4 112,219 Target Target CD254 9 5 0.00 -0.67 0.56 0.62
Epidermal Growth Factor Receptor 24,772 Target Disease Cancer 1,053,491 13,587 0.08 -0.67 0.55 0.66
ERK1 18,374 Target Target ERK2 3,287 1,788 0.23 -0.64 0.54 0.82
Maternal Embryonic Leucine Zipper Kinase 39 Target Disease Cancer 1,053,491 21 0.00 -0.68 0.54 0.58
Cytokeratin 20 847 Target Disease Carcinoma 433,099 449 0.02 -0.69 0.53 0.63
Eotaxin-3/CCL26 26 Target Target Eotaxin-2/CCL24 19 10 0.45 -0.54 0.53 0.94
CCL19 658 Target Target CCL21 808 344 0.47 -0.52 0.52 0.93
Epigen 27 Target Target EGF 27,487 14 0.02 -0.69 0.52 0.67
ANGPT1 81 Target Target ANGPT2 105 42 0.46 -0.54 0.52 0.94
CSF2/GM-CSF 2 Target Disease Infection 766,637 1 0.00 -0.71 0.50 0.57
Adp/Atp Translocase 3 2 Target Disease Breast Cancer 173,695 1 0.00 -0.71 0.50 0.60
Atp-Binding Cassette Sub-Family G Member 1 2 Target Disease Liver Disease 49,817 1 0.00 -0.71 0.50 0.62
EPHB3 118 Target Target EPHB2 385 59 0.28 -0.65 0.50 0.88
ADRBK2 8 Target Target Beta-Adrenergic Receptor Kinase 2 15 4 0.37 -0.61 0.50 0.93
BNP 6,842 Target Target Brain (B-type) Natriuretic Protein 8 4 0.02 -0.71 0.50 0.69
Alpha-Glucosidase 4,319 Target Drug Alglucosidase Alfa (Myozyme)- FDA 4 2 0.02 -0.71 0.50 0.69
CD4 112,219 Target Target Ck-beta-11 4 2 0.00 -0.71 0.50 0.61
CRG-2 41 Target Target CRG-10 2 1 0.11 -0.70 0.50 0.83
C7 7,027 Target Drug Kadangustin J 2 1 0.01 -0.71 0.50 0.67
Renin 43,456 Target Disease Hypertension (High Blood Pressure) 2 1 0.00 -0.71 0.50 0.62
CD4 112,219 Target Drug Actemra (Tocilizumab Injection)- FDA 2 1 0.00 -0.71 0.50 0.60
bFGF 9,327 Target Target aFGF 899 448 0.15 -0.69 0.50 0.79
CEA 17,022 Target Target CA 15-3 898 437 0.11 -0.71 0.49 0.76
CCL2 3,560 Target Target CCL8 197 92 0.11 -0.72 0.47 0.78
Erbb2 4,536 Target Target ERBB4 994 461 0.22 -0.69 0.46 0.83
Retinoic Acid Receptor Alpha 1,068 Target Disease Leukemia 162,805 490 0.04 -0.73 0.46 0.66
Vascular Cell Adhesion Protein 1 31 Target Disease Inflammation 252,734 14 0.01 -0.74 0.45 0.60
4-1BB Receptor 20 Target Target 4-1BB Ligand 135 9 0.17 -0.72 0.45 0.85
CD4 112,219 Target Target 4-1BB Receptor 20 9 0.01 -0.74 0.45 0.62
CINC-2- alpha 9 Target Disease Inflammation 252,734 4 0.00 -0.75 0.44 0.59
CXCL10/IP-10 114 Target Target CXCL4/PF4 9 4 0.12 -0.73 0.44 0.83
CCL5 2,002 Target Target CXCL4/PF4 9 4 0.03 -0.74 0.44 0.72
ANXA7 35 Target Disease Cancer 1,053,491 15 0.00 -0.76 0.43 0.57
Glutathione Transferase Omega-1 14 Target Disease Cancer 1,053,491 6 0.00 -0.76 0.43 0.57
AMY2B 21 Target Target Alpha-Amylase 7,171 9 0.02 -0.76 0.43 0.70
Calmodulin 25,240 Target Target CAMK2B 21 9 0.01 -0.76 0.43 0.66
Eotaxin 2,457 Target Disease Inflammation 252,734 1,048 0.04 -0.76 0.43 0.66
Angiotensin-Converting Enzyme 2 665 Target Target Renin 43,456 283 0.05 -0.76 0.43 0.70
BMP-6 386 Target Target BMP-2 3,889 163 0.13 -0.74 0.42 0.80
Sodium Channel Nav1.8 31 Target Disease Pain 409,851 13 0.00 -0.76 0.42 0.59
Angiostatin K1-3 17 Target Disease Cancer 1,053,491 7 0.00 -0.77 0.41 0.57