PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
DNAJB1 44 Target Disease Shock 134,031 18 0.01 -0.77 0.41 0.62
CCL18 256 Target Target DC-CK1 22 9 0.12 -0.76 0.41 0.82
CEA 17,022 Target Disease Cancer 1,053,491 6,937 0.05 -0.77 0.41 0.63
Dihydropteroate Synthase 408 Target Target Dihydrofolate Reductase 5,563 166 0.11 -0.76 0.41 0.78
Small Inducible Cytokine A2 5 Target Disease Inflammation 252,734 2 0.00 -0.77 0.40 0.59
Erbb2 4,536 Target Target Prostaglandin E2 Receptor Ep4 Subtype 5 2 0.01 -0.77 0.40 0.69
BRSK1 20 Target Disease Menopause 19,680 8 0.01 -0.77 0.40 0.66
ERBB4 994 Target Target ERBB3 1,154 394 0.37 -0.63 0.40 0.91
Androgen Receptor 12,918 Target Disease Cancer 1,053,491 5,102 0.04 -0.78 0.39 0.63
CCNB1 160 Target Disease Cancer 1,053,491 62 0.00 -0.78 0.39 0.58
CHK2 1,391 Target Target CHK1 2,044 533 0.32 -0.68 0.38 0.89
Erbb2 4,536 Target Disease Breast Cancer 173,695 1,718 0.06 -0.78 0.38 0.68
CD4 112,219 Target Target Exodus-3 8 3 0.00 -0.79 0.38 0.61
Androgen Receptor 12,918 Target Target Aldo-Keto Reductase Family 1 Member C3 8 3 0.01 -0.79 0.38 0.66
CCL4 5,638 Target Target CCL3 1,427 535 0.19 -0.75 0.37 0.83
CCL2 3,560 Target Target CCL3 1,427 533 0.24 -0.73 0.37 0.85
Epigen 27 Target Disease Cancer 1,053,491 10 0.00 -0.79 0.37 0.57
Collagen 138,882 Target Target CD-RAP 44 16 0.01 -0.80 0.36 0.62
Ns3 3,189 Target Disease Infection 766,637 1,156 0.02 -0.80 0.36 0.61
Collagenase-3 367 Target Target Collagen 138,882 132 0.02 -0.80 0.36 0.64
Collagen 138,882 Target Target Collagenase 3 367 132 0.02 -0.80 0.36 0.64
BAFF 1,240 Target Target BLyS 457 164 0.22 -0.75 0.36 0.86
BMP-14 14 Target Target BMP-2 3,889 5 0.02 -0.80 0.36 0.70
Epiregulin 291 Target Target beta-Cellulin 17 6 0.09 -0.80 0.35 0.80
CCL5 2,002 Target Target CCL3 1,427 500 0.30 -0.70 0.35 0.89
Cyclooxygenase-3 20 Target Target Cox-2 21,583 7 0.01 -0.81 0.35 0.66
APOA2 118 Target Disease Cholesterol 182,390 41 0.01 -0.81 0.35 0.62
Eotaxin-3/CCL26 26 Target Disease Inflammation 252,734 9 0.00 -0.81 0.35 0.60
Endostatin 1,599 Target Disease Cancer 1,053,491 544 0.01 -0.81 0.34 0.59
Cytokeratin 20 847 Target Disease Cancer 1,053,491 288 0.01 -0.81 0.34 0.59
CCL5 2,002 Target Target CCL2 3,560 673 0.25 -0.73 0.34 0.87
Tubulin Beta-1 Chain 3 Target Target Inosine-5'-Monophosphate Dehydrogenase 261 1 0.04 -0.81 0.33 0.76
Synaptic Vesicle Glycoprotein 2a 9 Target Disease Epilepsy 71,172 3 0.00 -0.82 0.33 0.62
Mu Opioid Receptor 4,576 Target Target CTAP-3 6 2 0.01 -0.82 0.33 0.68
Microsomal Glutathione S-Transferase 2 6 Target Disease Psoriasis 26,882 2 0.00 -0.82 0.33 0.64
Heat Shock Protein Hsp 90-Beta 3 Target Disease Cancer 1,053,491 1 0.00 -0.82 0.33 0.56
Heat Shock Protein Hsp 90-Beta 3 Target Disease Gastritis 17,713 1 0.00 -0.82 0.33 0.64
Glucocorticoid Receptor 10,306 Target Drug Aminoglutethimide (Cytadren)- FDA 3 1 0.01 -0.82 0.33 0.65
Enovin 3 Target Disease Inflammation 252,734 1 0.00 -0.82 0.33 0.58
Dipeptidyl Peptidase 3 3 Target Disease Cancer 1,053,491 1 0.00 -0.82 0.33 0.56
Dipeptidyl Peptidase 3 3 Target Disease Malaria 56,215 1 0.00 -0.82 0.33 0.61
Calmodulin 25,240 Target Target Tubulin Beta-1 Chain 3 1 0.00 -0.82 0.33 0.63
CXCL11 526 Target Target CXCL4/PF4 9 3 0.04 -0.81 0.33 0.76
CD4 112,219 Target Drug Acyclovir for Injection (Zovirax Injection)- FDA 3 1 0.00 -0.82 0.33 0.60
CCL3 1,427 Target Target CXCL4/PF4 9 3 0.03 -0.82 0.33 0.72
BMP-2B 18 Target Target Collagen 138,882 6 0.00 -0.82 0.33 0.61
BMP-2B 18 Target Target BMP-4 1,255 6 0.04 -0.81 0.33 0.74
Angiotensin Converting Enzyme 31,674 Target Drug Atacand (Candesartan Cilexetil)- FDA 3 1 0.00 -0.82 0.33 0.63
Alk Tyrosine Kinase Receptor 3 Target Disease Cancer 1,053,491 1 0.00 -0.82 0.33 0.56
Alk Tyrosine Kinase Receptor 3 Target Disease Lung Cancer 91,416 1 0.00 -0.82 0.33 0.60
ACRP30 102 Target Disease Obesity 138,233 34 0.01 -0.82 0.33 0.62
ApoE2 517 Target Disease Cholesterol 182,390 170 0.02 -0.82 0.33 0.64
Vanilloid Receptor 1 404 Target Disease Pain 409,851 132 0.01 -0.82 0.33 0.61
CXCL10/IP-10 114 Target Target CXCL9 1,016 37 0.11 -0.81 0.32 0.81
CCL2 3,560 Target Target CXCL10/IP-10 114 37 0.06 -0.82 0.32 0.75
Androgen Receptor 12,918 Target Disease Prostate Cancer 71,064 4,112 0.14 -0.80 0.32 0.76
BMP-4 1,255 Target Target BMP-2 3,889 399 0.18 -0.78 0.32 0.83
CXCL3 145 Target Disease Inflammation 252,734 46 0.01 -0.83 0.32 0.61
CD4 112,219 Target Target CD154 1,512 477 0.04 -0.83 0.32 0.67
EPHB2 385 Target Target EPHB1 137 43 0.19 -0.78 0.31 0.86
BD2 76 Target Target BD3 32 10 0.20 -0.77 0.31 0.88
CCL2 3,560 Target Disease Inflammation 252,734 1,105 0.04 -0.83 0.31 0.65
CCL7 274 Target Disease Inflammation 252,734 85 0.01 -0.83 0.31 0.62
AURKC 26 Target Disease Infertility 35,448 8 0.01 -0.83 0.31 0.64
Eotaxin 2,457 Target Disease Asthma 109,610 749 0.05 -0.83 0.30 0.68
CCL7 274 Target Target CCL8 197 60 0.26 -0.74 0.30 0.90
BMP-7 1,112 Target Target BMP-2 3,889 338 0.16 -0.80 0.30 0.82
CCL8 197 Target Disease Inflammation 252,734 59 0.01 -0.84 0.30 0.61
Neuropeptide S Receptor 77 Target Disease Asthma 109,610 23 0.01 -0.84 0.30 0.62
CCN5 57 Target Target CYR61 539 17 0.10 -0.82 0.30 0.81
Epigen 27 Target Target Epiregulin 291 8 0.09 -0.83 0.30 0.81
Epidermal Growth Factor Receptor 24,772 Target Target Epigen 27 8 0.01 -0.84 0.30 0.65
Epidermal Growth Factor Receptor 24,772 Target Target beta-Cellulin 17 5 0.01 -0.84 0.29 0.65
Endostatin 1,599 Target Target Angiostatin K1-3 17 5 0.03 -0.84 0.29 0.73
CD31/PECAM1 7 Target Target CD34 24,598 2 0.00 -0.85 0.29 0.64
Androgen Receptor 12,918 Target Drug Avodart (Dutasteride)- FDA 7 2 0.01 -0.85 0.29 0.65
AACT 109 Target Target Alpha-1 AntiChymotrypsin 1,460 31 0.08 -0.84 0.28 0.78
Estrogen Receptor Beta 1,924 Target Disease Cancer 1,053,491 543 0.01 -0.85 0.28 0.59
CCL5 2,002 Target Disease Inflammation 252,734 565 0.03 -0.85 0.28 0.64
Aldosterone Receptor 528 Target Target Renin 43,456 147 0.03 -0.85 0.28 0.68
Phosphodiesterase 4b 54 Target Disease Schizophrenia 77,034 15 0.01 -0.85 0.28 0.63
Des (1-3) IGF-I 191 Target Target Des (1-6) IGF-II 18 5 0.09 -0.84 0.28 0.81
5-Hydroxytryptamine 2b Receptor 18 Target Disease Heart Disease 118,291 5 0.00 -0.85 0.28 0.61
Angiotensin Converting Enzyme 31,674 Target Target Aldosterone Receptor 528 146 0.04 -0.85 0.28 0.69
CD4 112,219 Target Disease Infection 766,637 30,996 0.11 -0.83 0.28 0.68
Epidermal Growth Factor Receptor 24,772 Target Target Epiregulin 291 80 0.03 -0.85 0.27 0.69
ADSF 11 Target Target Adiponectin 11,994 3 0.01 -0.85 0.27 0.66
CD22 1,591 Target Disease Leukemia 162,805 430 0.03 -0.85 0.27 0.65
Dihydropteroate Synthase 408 Target Disease Malaria 56,215 110 0.02 -0.85 0.27 0.67
CA125 Antigen 78 Target Disease Carcinoma 433,099 21 0.00 -0.85 0.27 0.59
Lanosterol 14 Alpha-Demethylase 101 Target Disease Cholesterol 182,390 27 0.01 -0.86 0.27 0.61
CD4 112,219 Target Target 4-1BB Ligand 135 36 0.01 -0.86 0.27 0.63
APOE 12,771 Target Disease Cholesterol 182,390 3,396 0.07 -0.85 0.27 0.69
BMX 185 Target Target BTK 1,263 49 0.10 -0.84 0.26 0.80
ACRP30 102 Target Disease Diabetes 332,602 27 0.00 -0.86 0.26 0.59
CXCL10 2,386 Target Target CCL8 197 52 0.08 -0.85 0.26 0.77
Mu Opioid Receptor 4,576 Target Target Mu-Type Opioid Receptor 19 5 0.02 -0.86 0.26 0.69
Eotaxin-2/CCL24 19 Target Disease Inflammation 252,734 5 0.00 -0.86 0.26 0.59
AMAC-1 19 Target Disease Inflammation 252,734 5 0.00 -0.86 0.26 0.59
DDR2 194 Target Disease Cancer 1,053,491 51 0.00 -0.86 0.26 0.57