PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
CCL2 3,560 Target Target CXCL3 145 38 0.05 -0.85 0.26 0.75
BMP-6 386 Target Target BMP-4 1,255 101 0.15 -0.82 0.26 0.83
CD146 729 Target Target CD34 24,598 190 0.04 -0.86 0.26 0.71
Exodus-2 27 Target Target CCL21 808 7 0.05 -0.86 0.26 0.76
ELC 355 Target Target Exodus-2 27 7 0.07 -0.85 0.26 0.79
Calmodulin 25,240 Target Target DAPK2 27 7 0.01 -0.86 0.26 0.65
CD148 74 Target Target DEP-1 88 19 0.24 -0.76 0.26 0.90
Maternal Embryonic Leucine Zipper Kinase 39 Target Disease Glioblastoma 17,933 10 0.01 -0.86 0.26 0.66
CCL2 3,560 Target Target CXCL2 750 192 0.12 -0.84 0.26 0.80
CCL3 1,427 Target Disease Inflammation 252,734 365 0.02 -0.86 0.26 0.63
CD4 112,219 Target Target CD137 474 120 0.02 -0.86 0.25 0.64
CXCL9 1,016 Target Disease Inflammation 252,734 256 0.02 -0.86 0.25 0.63
Epidermal Growth Factor Receptor 24,772 Target Target ERBB3 1,154 289 0.05 -0.86 0.25 0.72
Xaa-Pro Dipeptidase 4 Target Disease Diabetic Nephropathy 12,496 1 0.00 -0.87 0.25 0.64
Xaa-Pro Dipeptidase 4 Target Target EGF 27,487 1 0.00 -0.87 0.25 0.62
Prostaglandin Reductase 1 8 Target Disease Inflammation 252,734 2 0.00 -0.87 0.25 0.58
Kappa-Type Opioid Receptor 4 Target Target Sphingosine 1-Phosphate Receptor 1 150 1 0.04 -0.86 0.25 0.77
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 Target Target Collagen 138,882 1 0.00 -0.87 0.25 0.59
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 Target Disease Inflammation 252,734 1 0.00 -0.87 0.25 0.58
Glutathione S-Transferase Mu 2 8 Target Disease Inflammation 252,734 2 0.00 -0.87 0.25 0.58
Estrogen Receptor Beta 1,924 Target Target Egl Nine Homolog 1 4 1 0.01 -0.87 0.25 0.69
Epidermal Growth Factor Receptor 24,772 Target Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.63
Ck-beta-11 4 Target Target Exodus-2 27 1 0.10 -0.85 0.25 0.84
Ck-beta-11 4 Target Disease Breast Cancer 173,695 1 0.00 -0.87 0.25 0.59
Ck-beta-11 4 Target Target CD34 24,598 1 0.00 -0.87 0.25 0.63
Ck-beta-11 4 Target Target Exodus-3 8 1 0.18 -0.81 0.25 0.89
CD62L/L-Selectin 8 Target Disease Cancer 1,053,491 2 0.00 -0.87 0.25 0.55
CCL4 5,638 Target Target CCBL1 4 1 0.01 -0.87 0.25 0.66
CCL2 3,560 Target Target CCL1 220 55 0.06 -0.86 0.25 0.76
Antithrombin 13,773 Target Drug Alprostadil Injection (Caverject)- FDA 4 1 0.00 -0.87 0.25 0.64
ADRBK2 8 Target Disease Cancer 1,053,491 2 0.00 -0.87 0.25 0.55
BMP-6 386 Target Target BMP-7 1,112 95 0.15 -0.83 0.25 0.84
CXCL10 2,386 Target Disease Inflammation 252,734 585 0.02 -0.87 0.25 0.64
4-1BB Ligand 135 Target Target CD137 474 33 0.13 -0.84 0.24 0.84
Myeloperoxidase 16,181 Target Disease Inflammation 252,734 3,923 0.06 -0.86 0.24 0.68
3-Phosphoinositide-Dependent Protein Kinase 1 230 Target Disease Cancer 1,053,491 55 0.00 -0.87 0.24 0.57
CXCL10/IP-10 114 Target Target CXCL11 526 27 0.11 -0.85 0.24 0.82
CCL5 2,002 Target Target CXCL10/IP-10 114 27 0.06 -0.87 0.24 0.76
Crth2 Receptor 51 Target Disease Inflammation 252,734 12 0.00 -0.87 0.24 0.59
CCL14 34 Target Disease Inflammation 252,734 8 0.00 -0.87 0.24 0.59
CCL5 2,002 Target Target CXCL10 2,386 464 0.21 -0.79 0.23 0.87
Aurora B kinase 415 Target Disease Cancer 1,053,491 96 0.00 -0.88 0.23 0.57
Antithrombin 13,773 Target Drug Angiomax (Bivalirudin)- FDA 13 3 0.01 -0.88 0.23 0.65
CCL5 2,002 Target Target CCL8 197 45 0.07 -0.87 0.23 0.78
CXCL11 526 Target Disease Inflammation 252,734 119 0.01 -0.88 0.23 0.61
DAPK2 27 Target Target DAPK1 205 6 0.08 -0.87 0.22 0.81
CXCL9 1,016 Target Target CXCL4/PF4 9 2 0.02 -0.88 0.22 0.72
CCL2 3,560 Target Target CXCL4/PF4 9 2 0.01 -0.88 0.22 0.68
BAFF 1,240 Target Target CD254 9 2 0.02 -0.88 0.22 0.72
Androgen Receptor 12,918 Target Drug Doxorubicin-Formaldehyde Conjugate 9 2 0.01 -0.88 0.22 0.65
CCL2 3,560 Target Target CXCL10 2,386 530 0.18 -0.81 0.22 0.85
CXCL10/IP-10 114 Target Disease Inflammation 252,734 25 0.00 -0.88 0.22 0.60
CCL7 274 Target Target CCL5 2,002 60 0.08 -0.87 0.22 0.79
Angiotensin Converting Enzyme 31,674 Target Target Renin 43,456 6,899 0.19 -0.81 0.22 0.81
EGF 27,487 Target Target ERBB3 1,154 251 0.04 -0.88 0.22 0.71
ACVR1B 23 Target Target Activin A 2,048 5 0.02 -0.88 0.22 0.72
CXCL16 341 Target Disease Inflammation 252,734 74 0.01 -0.88 0.22 0.61
Antithrombin 13,773 Target Target D-Dimer 6,185 1,337 0.14 -0.84 0.22 0.81
Glutathione Transferase Omega-1 14 Target Disease Breast Cancer 173,695 3 0.00 -0.89 0.21 0.59
Endostatin 1,599 Target Target Collagen 138,882 339 0.02 -0.89 0.21 0.65
APOA1 958 Target Target APOA2 118 25 0.07 -0.88 0.21 0.79
ERBB4 994 Target Target EGF 27,487 210 0.04 -0.88 0.21 0.70
Eotaxin-2/CCL24 19 Target Disease Asthma 109,610 4 0.00 -0.89 0.21 0.60
AMAC-1 19 Target Target CCL18 256 4 0.06 -0.88 0.21 0.79
AMAC-1 19 Target Target DC-CK1 22 4 0.20 -0.80 0.21 0.90
Macrophage Metalloelastase 100 Target Disease Inflammation 252,734 21 0.00 -0.89 0.21 0.60
Cysteinyl Leukotriene Receptor 2 24 Target Disease Inflammation 252,734 5 0.00 -0.89 0.21 0.58
ApoE4 1,525 Target Disease Cholesterol 182,390 316 0.02 -0.89 0.21 0.64
Annexin A1 406 Target Disease Inflammation 252,734 82 0.01 -0.89 0.20 0.61
Collagen 138,882 Target Target BMP-2 3,889 783 0.03 -0.89 0.20 0.66
Cox-2 21,583 Target Disease Inflammation 252,734 4,343 0.06 -0.89 0.20 0.68
Renin 43,456 Target Drug Avapro (Irbesartan)- FDA 5 1 0.00 -0.89 0.20 0.61
Nad-Dependent Protein Deacetylase Sirtuin-1 5 Target Target Collagen 138,882 1 0.00 -0.89 0.20 0.59
Hiv-1 Integrase 1,199 Target Drug Kadsurarin 5 1 0.01 -0.89 0.20 0.70
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target Glutathione S-Transferase A3 15 3 0.01 -0.89 0.20 0.67
D4-GDI 35 Target Disease Cancer 1,053,491 7 0.00 -0.89 0.20 0.55
Collapsin Response Mediator Protein-1 30 Target Disease Lung Cancer 91,416 6 0.00 -0.89 0.20 0.61
Calmodulin 25,240 Target Target Adp/Atp Translocase 1 5 1 0.00 -0.89 0.20 0.62
CD95 4,266 Target Target Apo I 55 11 0.02 -0.89 0.20 0.71
CCL5 2,002 Target Target Small Inducible Cytokine A2 5 1 0.01 -0.89 0.20 0.69
CCL2 3,560 Target Target Small Inducible Cytokine A2 5 1 0.01 -0.89 0.20 0.67
Angiotensin Converting Enzyme 31,674 Target Drug Avapro (Irbesartan)- FDA 5 1 0.00 -0.89 0.20 0.62
Androgen Receptor 12,918 Target Target ADRBK1 10 2 0.01 -0.89 0.20 0.65
ANXA7 35 Target Disease Prostate Cancer 71,064 7 0.00 -0.89 0.20 0.62
4-1BB Receptor 20 Target Target CD137 474 4 0.04 -0.89 0.20 0.76
CD1A 2,739 Target Target CD4 112,219 547 0.03 -0.89 0.20 0.66
Toll-Like Receptor 2 2,174 Target Disease Inflammation 252,734 434 0.02 -0.89 0.20 0.63
CXCL7 76 Target Target CCL2 3,560 15 0.03 -0.89 0.20 0.72
Histamine H4 Receptor 168 Target Disease Inflammation 252,734 33 0.01 -0.90 0.20 0.60
BMP-7 1,112 Target Target Collagen 138,882 215 0.02 -0.90 0.19 0.64
CCL3 1,427 Target Target CCL8 197 38 0.07 -0.89 0.19 0.78
Eotaxin-3/CCL26 26 Target Disease Asthma 109,610 5 0.00 -0.90 0.19 0.60
Epidermal Growth Factor Receptor 24,772 Target Target ERBB4 994 191 0.04 -0.90 0.19 0.70
BRK 236 Target Disease Breast Cancer 173,695 45 0.01 -0.90 0.19 0.61
Calmodulin 25,240 Target Target CAMK2D 21 4 0.01 -0.90 0.19 0.64
Epidermal Growth Factor Receptor 24,772 Target Target EGF 27,487 4,679 0.18 -0.82 0.19 0.82
CCL2 3,560 Target Target CXCL9 1,016 190 0.10 -0.88 0.19 0.80
CCL7 274 Target Target CCL3 1,427 51 0.08 -0.89 0.19 0.79
CCL7 274 Target Target CXCL10 2,386 51 0.06 -0.89 0.19 0.77
CA 72-4 184 Target Target CA 15-3 898 34 0.08 -0.89 0.18 0.80