PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
Collagenase-3 367 Target Target Collagenase 3 367 367 1.00 -0.00 1.00 1.00
Metabotropic Glutamate Receptor 1 221 Target Target Glutamate Receptor 1 352 221 0.79 -0.04 1.00 0.97
Exodus-2 27 Target Target Exodus-3 8 7 0.48 -0.30 0.88 0.92
CCL19 658 Target Target CCL21 808 344 0.47 -0.52 0.52 0.93
ANGPT1 81 Target Target ANGPT2 105 42 0.46 -0.54 0.52 0.94
Eotaxin-3/CCL26 26 Target Target Eotaxin-2/CCL24 19 10 0.45 -0.54 0.53 0.94
CXCL9 1,016 Target Target CXCL10 2,386 676 0.43 -0.49 0.67 0.90
CXCL9 1,016 Target Target CXCL11 526 293 0.40 -0.56 0.56 0.91
ApoE2 517 Target Target ApoE4 1,525 348 0.39 -0.50 0.67 0.89
ERBB4 994 Target Target ERBB3 1,154 394 0.37 -0.63 0.40 0.91
ADRBK2 8 Target Target Beta-Adrenergic Receptor Kinase 2 15 4 0.37 -0.61 0.50 0.93
CXCL11 526 Target Target CXCL10 2,386 369 0.33 -0.50 0.70 0.87
AKT2 873 Target Target AKT3 293 164 0.32 -0.60 0.56 0.88
CHK2 1,391 Target Target CHK1 2,044 533 0.32 -0.68 0.38 0.89
Erbb2 4,536 Target Target ERBB3 1,154 711 0.31 -0.57 0.62 0.86
CCL5 2,002 Target Target CCL3 1,427 500 0.30 -0.70 0.35 0.89
EPHB3 118 Target Target EPHB2 385 59 0.28 -0.65 0.50 0.88
CCL7 274 Target Target CCL8 197 60 0.26 -0.74 0.30 0.90
ApoE4 1,525 Target Target APOE 12,771 1,119 0.25 -0.49 0.73 0.82
CCL5 2,002 Target Target CCL2 3,560 673 0.25 -0.73 0.34 0.87
CXCL3 145 Target Target CXCL2 750 81 0.25 -0.63 0.56 0.86
Alpha-Amylase 7,171 Target Target Pancreatic Alpha-Amylase 423 423 0.24 -0.05 1.00 0.81
CCL2 3,560 Target Target CCL3 1,427 533 0.24 -0.73 0.37 0.85
CD148 74 Target Target DEP-1 88 19 0.24 -0.76 0.26 0.90
ERK1 18,374 Target Target ERK2 3,287 1,788 0.23 -0.64 0.54 0.82
CXCL10/IP-10 114 Target Target CXCL10 2,386 114 0.22 -0.09 1.00 0.82
BAFF 1,240 Target Target BLyS 457 164 0.22 -0.75 0.36 0.86
Erbb2 4,536 Target Target ERBB4 994 461 0.22 -0.69 0.46 0.83
CCL5 2,002 Target Target CXCL10 2,386 464 0.21 -0.79 0.23 0.87
Cathepsin G 1,613 Target Target Elastase 13,875 985 0.21 -0.60 0.61 0.81
BD2 76 Target Target BD3 32 10 0.20 -0.77 0.31 0.88
AMAC-1 19 Target Target DC-CK1 22 4 0.20 -0.80 0.21 0.90
Niemann Pick Disease 1,234 Disease Target Sphingomyelinase 3,060 369 0.19 -0.79 0.30 0.84
CCL4 5,638 Target Target CCL3 1,427 535 0.19 -0.75 0.37 0.83
EPHB2 385 Target Target EPHB1 137 43 0.19 -0.78 0.31 0.86
Angiotensin Converting Enzyme 31,674 Target Target Renin 43,456 6,899 0.19 -0.81 0.22 0.81
Acute Promyelocytic Leukemia 4,780 Disease Target Retinoic Acid Receptor Alpha 1,068 413 0.18 -0.75 0.39 0.82
CCL2 3,560 Target Target CXCL10 2,386 530 0.18 -0.81 0.22 0.85
BMP-4 1,255 Target Target BMP-2 3,889 399 0.18 -0.78 0.32 0.83
Epidermal Growth Factor Receptor 24,772 Target Target EGF 27,487 4,679 0.18 -0.82 0.19 0.82
Ck-beta-11 4 Target Target Exodus-3 8 1 0.18 -0.81 0.25 0.89
ApoE2 517 Target Target APOE 12,771 454 0.18 -0.34 0.88 0.78
4-1BB Receptor 20 Target Target 4-1BB Ligand 135 9 0.17 -0.72 0.45 0.85
CCL7 274 Target Target CCL2 3,560 164 0.17 -0.62 0.60 0.81
BMP-7 1,112 Target Target BMP-2 3,889 338 0.16 -0.80 0.30 0.82
Alpha-Glucosidase 4,319 Target Target Lysosomal Alpha-Glucosidase 105 105 0.16 -0.10 1.00 0.79
bFGF 9,327 Target Target aFGF 899 448 0.15 -0.69 0.50 0.79
D(1a) Dopamine Receptor 51 Target Target D(2) Dopamine Receptor 1,559 41 0.15 -0.44 0.80 0.80
BMP-6 386 Target Target BMP-4 1,255 101 0.15 -0.82 0.26 0.83
BMP-6 386 Target Target BMP-7 1,112 95 0.15 -0.83 0.25 0.84
Angiotensin Converting Enzyme 31,674 Target Target Angiotensin-Converting Enzyme 2 665 665 0.14 -0.04 1.00 0.76
Antithrombin 13,773 Target Target D-Dimer 6,185 1,337 0.14 -0.84 0.22 0.81
Retinitis 9,116 Disease Target ADRP 537 317 0.14 -0.63 0.59 0.78
BMP-7 1,112 Target Target BMP-4 1,255 169 0.14 -0.86 0.15 0.85
BAFF 1,240 Target Target BAFFR 44 33 0.14 -0.49 0.75 0.80
Tissue-Type Plasminogen Activator 5,020 Target Target Urokinase-Type Plasminogen Activator 3,939 603 0.14 -0.86 0.15 0.83
EPHB3 118 Target Target EPHB1 137 17 0.13 -0.87 0.14 0.87
BMP-6 386 Target Target BMP-2 3,889 163 0.13 -0.74 0.42 0.80
4-1BB Ligand 135 Target Target CD137 474 33 0.13 -0.84 0.24 0.84
CCL3 1,427 Target Target CXCL10 2,386 238 0.13 -0.87 0.17 0.83
Artemin 184 Target Target Enovin 3 3 0.13 -0.50 1.00 0.81
CCL5 2,002 Target Target CXCL9 1,016 180 0.13 -0.87 0.18 0.83
CXCL10/IP-10 114 Target Target CXCL4/PF4 9 4 0.12 -0.73 0.44 0.83
Bile Salt Export Pump 476 Target Target Multidrug Resistance-Associated Protein 2 462 57 0.12 -0.88 0.12 0.85
AMY2B 21 Target Target AMY1A 13 2 0.12 -0.87 0.15 0.87
CCL18 256 Target Target DC-CK1 22 9 0.12 -0.76 0.41 0.82
CCL3 1,427 Target Target CXCL2 750 123 0.12 -0.87 0.16 0.83
CCL2 3,560 Target Target CXCL2 750 192 0.12 -0.84 0.26 0.80
CEA 17,022 Target Target CA 15-3 898 437 0.11 -0.71 0.49 0.76
Angiomax (Bivalirudin)- FDA 13 Drug Target Bivalirudin 891 12 0.11 -0.28 0.92 0.79
CRG-2 41 Target Target CRG-10 2 1 0.11 -0.70 0.50 0.83
CXCL10/IP-10 114 Target Target CXCL11 526 27 0.11 -0.85 0.24 0.82
Dihydropteroate Synthase 408 Target Target Dihydrofolate Reductase 5,563 166 0.11 -0.76 0.41 0.78
CCL2 3,560 Target Target CCL8 197 92 0.11 -0.72 0.47 0.78
CD1A 2,739 Target Target CD68 6,424 458 0.11 -0.88 0.17 0.80
CXCL10/IP-10 114 Target Target CXCL9 1,016 37 0.11 -0.81 0.32 0.81
BD3 32 Target Target BD4 26 3 0.10 -0.90 0.12 0.86
Eotaxin 2,457 Target Target Eotaxin-3/CCL26 26 26 0.10 -0.19 1.00 0.77
BMX 185 Target Target BTK 1,263 49 0.10 -0.84 0.26 0.80
CCL2 3,560 Target Target CXCL9 1,016 190 0.10 -0.88 0.19 0.80
Ent2 108 Target Target Equilibrative Nucleoside Transporter 1 211 15 0.10 -0.89 0.14 0.84
CXCL9 1,016 Target Target CCL3 1,427 117 0.10 -0.90 0.12 0.82
CCN5 57 Target Target CYR61 539 17 0.10 -0.82 0.30 0.81
Ck-beta-11 4 Target Target Exodus-2 27 1 0.10 -0.85 0.25 0.84
EPHB4 329 Target Target EPHB2 385 34 0.10 -0.90 0.10 0.84
Obesity 138,233 Disease Target Adiponectin 11,994 3,886 0.10 -0.81 0.32 0.72
CCL4 5,638 Target Target CCL5 2,002 316 0.09 -0.89 0.16 0.79
ELC 355 Target Target Exodus-3 8 5 0.09 -0.61 0.62 0.79
Platelet Aggregation 25,460 Disease Target Collagen 138,882 5,467 0.09 -0.87 0.21 0.72
EPHB4 329 Target Target EPHB3 118 18 0.09 -0.90 0.15 0.82
FABP3 134 Target Target FABP1 90 10 0.09 -0.91 0.11 0.84
Epigen 27 Target Target Epiregulin 291 8 0.09 -0.83 0.30 0.81
Mu Opioid Receptor 4,576 Target Target Opioid Receptor Mu 71 51 0.09 -0.53 0.72 0.76
CKMM 55 Target Target CKBB 57 5 0.09 -0.91 0.09 0.86
Eotaxin 2,457 Target Target Eotaxin-2/CCL24 19 19 0.09 -0.22 1.00 0.76
CD1A 2,739 Target Target CD14 9,941 456 0.09 -0.89 0.17 0.77
CXCL7 76 Target Target CXCL3 145 9 0.09 -0.91 0.12 0.84
Epiregulin 291 Target Target beta-Cellulin 17 6 0.09 -0.80 0.35 0.80
Des (1-3) IGF-I 191 Target Target Des (1-6) IGF-II 18 5 0.09 -0.84 0.28 0.81
CA 72-4 184 Target Target CA 15-3 898 34 0.08 -0.89 0.18 0.80