PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
Collagenase-3 367 Target Target Collagenase 3 367 367 1.00 -0.00 1.00 1.00
Angiotensin Converting Enzyme 31,674 Target Target Angiotensin-Converting Enzyme 2 665 665 0.14 -0.04 1.00 0.76
Metabotropic Glutamate Receptor 1 221 Target Target Glutamate Receptor 1 352 221 0.79 -0.04 1.00 0.97
Alpha-Amylase 7,171 Target Target Pancreatic Alpha-Amylase 423 423 0.24 -0.05 1.00 0.81
CXCL10/IP-10 114 Target Target CXCL10 2,386 114 0.22 -0.09 1.00 0.82
Alpha-Glucosidase 4,319 Target Target Lysosomal Alpha-Glucosidase 105 105 0.16 -0.10 1.00 0.79
Eotaxin 2,457 Target Target Eotaxin-3/CCL26 26 26 0.10 -0.19 1.00 0.77
Eotaxin 2,457 Target Target Eotaxin-2/CCL24 19 19 0.09 -0.22 1.00 0.76
Exodus-2 27 Target Target Exodus-3 8 7 0.48 -0.30 0.88 0.92
ApoE2 517 Target Target APOE 12,771 454 0.18 -0.34 0.88 0.78
Neutral Alpha-Glucosidase C 6 Target Target Alpha-Glucosidase 4,319 6 0.04 -0.38 1.00 0.72
D(1a) Dopamine Receptor 51 Target Target D(2) Dopamine Receptor 1,559 41 0.15 -0.44 0.80 0.80
CD4 112,219 Target Target CCL27/CTACK 5 4 0.01 -0.45 0.80 0.62
CD4 112,219 Target Target CTLA-4/Fc 4 4 0.01 -0.45 1.00 0.62
CXCL9 1,016 Target Target CXCL10 2,386 676 0.43 -0.49 0.67 0.90
ApoE4 1,525 Target Target APOE 12,771 1,119 0.25 -0.49 0.73 0.82
BAFF 1,240 Target Target BAFFR 44 33 0.14 -0.49 0.75 0.80
Artemin 184 Target Target Enovin 3 3 0.13 -0.50 1.00 0.81
ELC 355 Target Target Ck-beta-11 4 3 0.08 -0.50 0.75 0.78
ApoE2 517 Target Target ApoE4 1,525 348 0.39 -0.50 0.67 0.89
CXCL11 526 Target Target CXCL10 2,386 369 0.33 -0.50 0.70 0.87
CCL19 658 Target Target CCL21 808 344 0.47 -0.52 0.52 0.93
Mu Opioid Receptor 4,576 Target Target Opioid Receptor Mu 71 51 0.09 -0.53 0.72 0.76
ANGPT1 81 Target Target ANGPT2 105 42 0.46 -0.54 0.52 0.94
Eotaxin-3/CCL26 26 Target Target Eotaxin-2/CCL24 19 10 0.45 -0.54 0.53 0.94
ACRP30 102 Target Target Adiponectin 11,994 72 0.07 -0.54 0.71 0.73
EGF 27,487 Target Target beta-Cellulin 17 12 0.02 -0.54 0.71 0.67
CD14 9,941 Target Target Endotoxin receptor 115 80 0.07 -0.55 0.70 0.74
Calmodulin 25,240 Target Target CAMK4 43 30 0.03 -0.55 0.70 0.69
Alpha-Amylase 7,171 Target Target AMY1A 13 9 0.03 -0.55 0.69 0.70
CXCL9 1,016 Target Target CXCL11 526 293 0.40 -0.56 0.56 0.91
Erbb2 4,536 Target Target ERBB3 1,154 711 0.31 -0.57 0.62 0.86
APOE 12,771 Target Target APOC1 126 82 0.06 -0.59 0.65 0.73
AKT2 873 Target Target AKT3 293 164 0.32 -0.60 0.56 0.88
Cathepsin G 1,613 Target Target Elastase 13,875 985 0.21 -0.60 0.61 0.81
ADRBK2 8 Target Target Beta-Adrenergic Receptor Kinase 2 15 4 0.37 -0.61 0.50 0.93
ELC 355 Target Target Exodus-3 8 5 0.09 -0.61 0.62 0.79
CCL7 274 Target Target CCL2 3,560 164 0.17 -0.62 0.60 0.81
CXCL3 145 Target Target CXCL2 750 81 0.25 -0.63 0.56 0.86
ERBB4 994 Target Target ERBB3 1,154 394 0.37 -0.63 0.40 0.91
Adenosine Deaminase 6,613 Target Target ADAT1 5 3 0.02 -0.63 0.60 0.69
CEA 17,022 Target Target CA 72-4 184 108 0.06 -0.64 0.59 0.72
ERK1 18,374 Target Target ERK2 3,287 1,788 0.23 -0.64 0.54 0.82
DDR2 194 Target Target Collagen 138,882 113 0.02 -0.65 0.58 0.65
EPHB3 118 Target Target EPHB2 385 59 0.28 -0.65 0.50 0.88
Epiregulin 291 Target Target EGF 27,487 162 0.06 -0.66 0.56 0.71
CXCL10 2,386 Target Target CXCL4/PF4 9 5 0.03 -0.67 0.56 0.72
CD4 112,219 Target Target CD254 9 5 0.00 -0.67 0.56 0.62
CHK2 1,391 Target Target CHK1 2,044 533 0.32 -0.68 0.38 0.89
bFGF 9,327 Target Target aFGF 899 448 0.15 -0.69 0.50 0.79
Epigen 27 Target Target EGF 27,487 14 0.02 -0.69 0.52 0.67
Erbb2 4,536 Target Target ERBB4 994 461 0.22 -0.69 0.46 0.83
CCL5 2,002 Target Target CCL3 1,427 500 0.30 -0.70 0.35 0.89
CRG-2 41 Target Target CRG-10 2 1 0.11 -0.70 0.50 0.83
BNP 6,842 Target Target Brain (B-type) Natriuretic Protein 8 4 0.02 -0.71 0.50 0.69
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target C1orf41 1 1 0.01 -0.71 1.00 0.68
BNP 6,842 Target Target BNP/NPPB 1 1 0.01 -0.71 1.00 0.68
CD4 112,219 Target Target Ck-beta-11 4 2 0.00 -0.71 0.50 0.61
CEA 17,022 Target Target CA 15-3 898 437 0.11 -0.71 0.49 0.76
4-1BB Receptor 20 Target Target 4-1BB Ligand 135 9 0.17 -0.72 0.45 0.85
CCL2 3,560 Target Target CCL8 197 92 0.11 -0.72 0.47 0.78
CCL2 3,560 Target Target CCL3 1,427 533 0.24 -0.73 0.37 0.85
CXCL10/IP-10 114 Target Target CXCL4/PF4 9 4 0.12 -0.73 0.44 0.83
CCL5 2,002 Target Target CCL2 3,560 673 0.25 -0.73 0.34 0.87
CCL7 274 Target Target CCL8 197 60 0.26 -0.74 0.30 0.90
CD4 112,219 Target Target 4-1BB Receptor 20 9 0.01 -0.74 0.45 0.62
BMP-6 386 Target Target BMP-2 3,889 163 0.13 -0.74 0.42 0.80
CCL5 2,002 Target Target CXCL4/PF4 9 4 0.03 -0.74 0.44 0.72
BAFF 1,240 Target Target BLyS 457 164 0.22 -0.75 0.36 0.86
CCL4 5,638 Target Target CCL3 1,427 535 0.19 -0.75 0.37 0.83
CCL18 256 Target Target DC-CK1 22 9 0.12 -0.76 0.41 0.82
Angiotensin-Converting Enzyme 2 665 Target Target Renin 43,456 283 0.05 -0.76 0.43 0.70
AMY2B 21 Target Target Alpha-Amylase 7,171 9 0.02 -0.76 0.43 0.70
Calmodulin 25,240 Target Target CAMK2B 21 9 0.01 -0.76 0.43 0.66
Dihydropteroate Synthase 408 Target Target Dihydrofolate Reductase 5,563 166 0.11 -0.76 0.41 0.78
CD148 74 Target Target DEP-1 88 19 0.24 -0.76 0.26 0.90
BD2 76 Target Target BD3 32 10 0.20 -0.77 0.31 0.88
Erbb2 4,536 Target Target Prostaglandin E2 Receptor Ep4 Subtype 5 2 0.01 -0.77 0.40 0.69
EPHB2 385 Target Target EPHB1 137 43 0.19 -0.78 0.31 0.86
BMP-4 1,255 Target Target BMP-2 3,889 399 0.18 -0.78 0.32 0.83
CCL5 2,002 Target Target CXCL10 2,386 464 0.21 -0.79 0.23 0.87
Androgen Receptor 12,918 Target Target Aldo-Keto Reductase Family 1 Member C3 8 3 0.01 -0.79 0.38 0.66
CD4 112,219 Target Target Exodus-3 8 3 0.00 -0.79 0.38 0.61
Epiregulin 291 Target Target beta-Cellulin 17 6 0.09 -0.80 0.35 0.80
BMP-7 1,112 Target Target BMP-2 3,889 338 0.16 -0.80 0.30 0.82
Collagen 138,882 Target Target CD-RAP 44 16 0.01 -0.80 0.36 0.62
Collagenase-3 367 Target Target Collagen 138,882 132 0.02 -0.80 0.36 0.64
Collagen 138,882 Target Target Collagenase 3 367 132 0.02 -0.80 0.36 0.64
BMP-14 14 Target Target BMP-2 3,889 5 0.02 -0.80 0.36 0.70
AMAC-1 19 Target Target DC-CK1 22 4 0.20 -0.80 0.21 0.90
Cyclooxygenase-3 20 Target Target Cox-2 21,583 7 0.01 -0.81 0.35 0.66
CXCL10/IP-10 114 Target Target CXCL9 1,016 37 0.11 -0.81 0.32 0.81
Ck-beta-11 4 Target Target Exodus-3 8 1 0.18 -0.81 0.25 0.89
Angiotensin Converting Enzyme 31,674 Target Target Renin 43,456 6,899 0.19 -0.81 0.22 0.81
CCL2 3,560 Target Target CXCL10 2,386 530 0.18 -0.81 0.22 0.85
CXCL11 526 Target Target CXCL4/PF4 9 3 0.04 -0.81 0.33 0.76
BMP-2B 18 Target Target BMP-4 1,255 6 0.04 -0.81 0.33 0.74
Tubulin Beta-1 Chain 3 Target Target Inosine-5'-Monophosphate Dehydrogenase 261 1 0.04 -0.81 0.33 0.76
CCL3 1,427 Target Target CXCL4/PF4 9 3 0.03 -0.82 0.33 0.72
Mu Opioid Receptor 4,576 Target Target CTAP-3 6 2 0.01 -0.82 0.33 0.68