PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
Tuberculosis 146,217 Disease Target Udp-N-Acetylmuramoylalanine--D-Glutamate Ligase 1 1 0.00 -0.71 1.00 0.61
Shock 134,031 Disease Target C1orf41 1 1 0.00 -0.71 1.00 0.61
Neutral Alpha-Glucosidase C 6 Target Target Alpha-Glucosidase 4,319 6 0.04 -0.38 1.00 0.72
Metabotropic Glutamate Receptor 1 221 Target Target Glutamate Receptor 1 352 221 0.79 -0.04 1.00 0.97
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target C1orf41 1 1 0.01 -0.71 1.00 0.68
Eotaxin 2,457 Target Target Eotaxin-3/CCL26 26 26 0.10 -0.19 1.00 0.77
Eotaxin 2,457 Target Target Eotaxin-2/CCL24 19 19 0.09 -0.22 1.00 0.76
Diabetes 332,602 Disease Target BNP/NPPB 1 1 0.00 -0.71 1.00 0.59
Collagenase-3 367 Target Target Collagenase 3 367 367 1.00 -0.00 1.00 1.00
CXCL10/IP-10 114 Target Target CXCL10 2,386 114 0.22 -0.09 1.00 0.82
CD4 112,219 Target Target CTLA-4/Fc 4 4 0.01 -0.45 1.00 0.62
BNP 6,842 Target Target BNP/NPPB 1 1 0.01 -0.71 1.00 0.68
Artemin 184 Target Target Enovin 3 3 0.13 -0.50 1.00 0.81
Argatroban Injection (Argatroban)- FDA 1 Drug Target Antithrombin 13,773 1 0.01 -0.71 1.00 0.66
Argatroban (Argatroban Injection)- FDA 1 Drug Target Antithrombin 13,773 1 0.01 -0.71 1.00 0.66
Antihemophilic Factor (Alphanate)- FDA 1 Drug Target Collagen 138,882 1 0.00 -0.71 1.00 0.61
Angiotensin Converting Enzyme 31,674 Target Target Angiotensin-Converting Enzyme 2 665 665 0.14 -0.04 1.00 0.76
Alphanate (Antihemophilic Factor)- FDA 1 Drug Target Collagen 138,882 1 0.00 -0.71 1.00 0.61
Alpha-Glucosidase 4,319 Target Target Lysosomal Alpha-Glucosidase 105 105 0.16 -0.10 1.00 0.79
Alpha-Amylase 7,171 Target Target Pancreatic Alpha-Amylase 423 423 0.24 -0.05 1.00 0.81
Angiomax (Bivalirudin)- FDA 13 Drug Target Bivalirudin 891 12 0.11 -0.28 0.92 0.79
ApoE2 517 Target Target APOE 12,771 454 0.18 -0.34 0.88 0.78
Exodus-2 27 Target Target Exodus-3 8 7 0.48 -0.30 0.88 0.92
D(1a) Dopamine Receptor 51 Target Target D(2) Dopamine Receptor 1,559 41 0.15 -0.44 0.80 0.80
Kadsurenone 70 Drug Target Platelet Activating Factor 9,915 56 0.07 -0.45 0.80 0.73
CD4 112,219 Target Target CCL27/CTACK 5 4 0.01 -0.45 0.80 0.62
Cancer 1,053,491 Disease Target CA 15-3 898 698 0.02 -0.47 0.78 0.61
Diabetes 332,602 Disease Target CAMK1D 21 16 0.01 -0.49 0.76 0.61
ELC 355 Target Target Ck-beta-11 4 3 0.08 -0.50 0.75 0.78
Cancer 1,053,491 Disease Target Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 3 0.00 -0.50 0.75 0.57
Cancer 1,053,491 Disease Target Aldo-Keto Reductase Family 1 Member C3 8 6 0.00 -0.50 0.75 0.58
BAFF 1,240 Target Target BAFFR 44 33 0.14 -0.49 0.75 0.80
ApoE4 1,525 Target Target APOE 12,771 1,119 0.25 -0.49 0.73 0.82
Mu Opioid Receptor 4,576 Target Target Opioid Receptor Mu 71 51 0.09 -0.53 0.72 0.76
EGF 27,487 Target Target beta-Cellulin 17 12 0.02 -0.54 0.71 0.67
ACRP30 102 Target Target Adiponectin 11,994 72 0.07 -0.54 0.71 0.73
CXCL11 526 Target Target CXCL10 2,386 369 0.33 -0.50 0.70 0.87
Calmodulin 25,240 Target Target CAMK4 43 30 0.03 -0.55 0.70 0.69
CD14 9,941 Target Target Endotoxin receptor 115 80 0.07 -0.55 0.70 0.74
Alpha-Amylase 7,171 Target Target AMY1A 13 9 0.03 -0.55 0.69 0.70
Cholesterol 182,390 Disease Target Squalene Monooxygenase 28 19 0.01 -0.57 0.68 0.62
ApoE2 517 Target Target ApoE4 1,525 348 0.39 -0.50 0.67 0.89
N-Heptanoyl-L-Homoserine Lactone 3 Drug Target C7 7,027 2 0.01 -0.58 0.67 0.68
CXCL9 1,016 Target Target CXCL10 2,386 676 0.43 -0.49 0.67 0.90
APOE 12,771 Target Target APOC1 126 82 0.06 -0.59 0.65 0.73
ELC 355 Target Target Exodus-3 8 5 0.09 -0.61 0.62 0.79
Cancer 1,053,491 Disease Target Erbb2 4,536 2,833 0.04 -0.61 0.62 0.63
Erbb2 4,536 Target Target ERBB3 1,154 711 0.31 -0.57 0.62 0.86
Cathepsin G 1,613 Target Target Elastase 13,875 985 0.21 -0.60 0.61 0.81
Cancer 1,053,491 Disease Target CA 72-4 184 112 0.01 -0.63 0.61 0.59
Adenosine Deaminase 6,613 Target Target ADAT1 5 3 0.02 -0.63 0.60 0.69
CCL7 274 Target Target CCL2 3,560 164 0.17 -0.62 0.60 0.81
Retinitis 9,116 Disease Target ADRP 537 317 0.14 -0.63 0.59 0.78
CEA 17,022 Target Target CA 72-4 184 108 0.06 -0.64 0.59 0.72
DDR2 194 Target Target Collagen 138,882 113 0.02 -0.65 0.58 0.65
Carcinoma 433,099 Disease Target Ret Proto-Oncogene 1,005 580 0.03 -0.65 0.58 0.63
AKT2 873 Target Target AKT3 293 164 0.32 -0.60 0.56 0.88
CXCL3 145 Target Target CXCL2 750 81 0.25 -0.63 0.56 0.86
CXCL9 1,016 Target Target CXCL11 526 293 0.40 -0.56 0.56 0.91
Epiregulin 291 Target Target EGF 27,487 162 0.06 -0.66 0.56 0.71
CXCL10 2,386 Target Target CXCL4/PF4 9 5 0.03 -0.67 0.56 0.72
CD4 112,219 Target Target CD254 9 5 0.00 -0.67 0.56 0.62
ERK1 18,374 Target Target ERK2 3,287 1,788 0.23 -0.64 0.54 0.82
Cancer 1,053,491 Disease Target Carbonic Anhydrase 9 150 80 0.01 -0.68 0.53 0.59
Infection 766,637 Disease Target Tegument Protein Vp16 19 10 0.00 -0.69 0.53 0.58
Eotaxin-3/CCL26 26 Target Target Eotaxin-2/CCL24 19 10 0.45 -0.54 0.53 0.94
Cancer 1,053,491 Disease Target Kallikrein-8 19 10 0.00 -0.69 0.53 0.57
Cancer 1,053,491 Disease Target Aurora Kinase A 196 103 0.01 -0.69 0.53 0.59
CCL19 658 Target Target CCL21 808 344 0.47 -0.52 0.52 0.93
Epigen 27 Target Target EGF 27,487 14 0.02 -0.69 0.52 0.67
ANGPT1 81 Target Target ANGPT2 105 42 0.46 -0.54 0.52 0.94
Sever Condition 2 Disease Target Ret Proto-Oncogene 1,005 1 0.02 -0.71 0.50 0.72
Prostate Cancer 71,064 Disease Target Aldo-Keto Reductase Family 1 Member C3 8 4 0.01 -0.71 0.50 0.63
EPHB3 118 Target Target EPHB2 385 59 0.28 -0.65 0.50 0.88
Drofenine 2 Drug Target BCHE 1,167 1 0.02 -0.71 0.50 0.72
Cholesterol 182,390 Disease Target Atp-Binding Cassette Sub-Family G Member 1 2 1 0.00 -0.71 0.50 0.59
Cancer 1,053,491 Disease Target Adp/Atp Translocase 3 2 1 0.00 -0.71 0.50 0.56
Cancer 1,053,491 Disease Target Prostaglandin Reductase 1 8 4 0.00 -0.71 0.50 0.57
CRG-2 41 Target Target CRG-10 2 1 0.11 -0.70 0.50 0.83
CD4 112,219 Target Target Ck-beta-11 4 2 0.00 -0.71 0.50 0.61
BNP 6,842 Target Target Brain (B-type) Natriuretic Protein 8 4 0.02 -0.71 0.50 0.69
ADRBK2 8 Target Target Beta-Adrenergic Receptor Kinase 2 15 4 0.37 -0.61 0.50 0.93
bFGF 9,327 Target Target aFGF 899 448 0.15 -0.69 0.50 0.79
Cancer 1,053,491 Disease Target APO-2L 90 44 0.00 -0.71 0.49 0.58
CEA 17,022 Target Target CA 15-3 898 437 0.11 -0.71 0.49 0.76
Cancer 1,053,491 Disease Target BRAF 4,766 2,231 0.03 -0.73 0.47 0.62
CCL2 3,560 Target Target CCL8 197 92 0.11 -0.72 0.47 0.78
Erbb2 4,536 Target Target ERBB4 994 461 0.22 -0.69 0.46 0.83
Cancer 1,053,491 Disease Target DAPK1 205 94 0.01 -0.74 0.46 0.58
Diabetes 332,602 Disease Target Exendin-4 855 392 0.02 -0.74 0.46 0.63
Schizophrenia 77,034 Disease Target Metabotropic Glutamate Receptor 3 55 25 0.01 -0.74 0.45 0.64
CD4 112,219 Target Target 4-1BB Receptor 20 9 0.01 -0.74 0.45 0.62
4-1BB Receptor 20 Target Target 4-1BB Ligand 135 9 0.17 -0.72 0.45 0.85
Cancer 1,053,491 Disease Target EPHA2 532 239 0.01 -0.74 0.45 0.59
CXCL10/IP-10 114 Target Target CXCL4/PF4 9 4 0.12 -0.73 0.44 0.83
CCL5 2,002 Target Target CXCL4/PF4 9 4 0.03 -0.74 0.44 0.72
Cancer 1,053,491 Disease Target Kallikrein-6 79 35 0.00 -0.75 0.44 0.58
Anxiety 113,510 Disease Target Neuropeptide S Receptor 77 34 0.01 -0.75 0.44 0.63
Arixtra (Fondaparinux Sodium)- FDA 16 Drug Target Antithrombin 13,773 7 0.01 -0.75 0.44 0.67
Carcinoma 433,099 Disease Target CXCL14/BRAK 7 3 0.00 -0.76 0.43 0.58