PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
Calmodulin 25,240 Target Target CAMK2B 21 9 0.01 -0.76 0.43 0.66
AMY2B 21 Target Target Alpha-Amylase 7,171 9 0.02 -0.76 0.43 0.70
Angiotensin-Converting Enzyme 2 665 Target Target Renin 43,456 283 0.05 -0.76 0.43 0.70
BMP-6 386 Target Target BMP-2 3,889 163 0.13 -0.74 0.42 0.80
Cancer 1,053,491 Disease Target ERBB3 1,154 481 0.01 -0.76 0.42 0.60
CCL18 256 Target Target DC-CK1 22 9 0.12 -0.76 0.41 0.82
Dihydropteroate Synthase 408 Target Target Dihydrofolate Reductase 5,563 166 0.11 -0.76 0.41 0.78
Erbb2 4,536 Target Target Prostaglandin E2 Receptor Ep4 Subtype 5 2 0.01 -0.77 0.40 0.69
Cancer 1,053,491 Disease Target AKT3 293 117 0.01 -0.77 0.40 0.58
ERBB4 994 Target Target ERBB3 1,154 394 0.37 -0.63 0.40 0.91
Inflammation 252,734 Disease Target CXCL2 750 291 0.02 -0.78 0.39 0.64
Acute Promyelocytic Leukemia 4,780 Disease Target Retinoic Acid Receptor Alpha 1,068 413 0.18 -0.75 0.39 0.82
Cancer 1,053,491 Disease Target Insulin-Like Growth Factor 1 Receptor 1,052 405 0.01 -0.78 0.38 0.59
Nephropathy Diabetic 13 Disease Target Renin 43,456 5 0.01 -0.78 0.38 0.64
Cancer 1,053,491 Disease Target CHK2 1,391 533 0.01 -0.79 0.38 0.60
CHK2 1,391 Target Target CHK1 2,044 533 0.32 -0.68 0.38 0.89
Androgen Receptor 12,918 Target Target Aldo-Keto Reductase Family 1 Member C3 8 3 0.01 -0.79 0.38 0.66
CD4 112,219 Target Target Exodus-3 8 3 0.00 -0.79 0.38 0.61
CCL4 5,638 Target Target CCL3 1,427 535 0.19 -0.75 0.37 0.83
CCL2 3,560 Target Target CCL3 1,427 533 0.24 -0.73 0.37 0.85
Cancer 1,053,491 Disease Target Aurora A kinase 318 118 0.01 -0.79 0.37 0.58
Obesity 138,233 Disease Target Melanin-Concentrating Hormone Receptor 1 143 53 0.01 -0.79 0.37 0.63
Cancer 1,053,491 Disease Target Multidrug Resistance Protein 1 495 183 0.01 -0.79 0.37 0.59
Collagen 138,882 Target Target CD-RAP 44 16 0.01 -0.80 0.36 0.62
Carcinoma 433,099 Disease Target Carbonic Anhydrase 9 150 54 0.01 -0.80 0.36 0.60
Collagenase-3 367 Target Target Collagen 138,882 132 0.02 -0.80 0.36 0.64
Collagen 138,882 Target Target Collagenase 3 367 132 0.02 -0.80 0.36 0.64
BAFF 1,240 Target Target BLyS 457 164 0.22 -0.75 0.36 0.86
Carcinoma 433,099 Disease Target AFP 9,751 3,499 0.05 -0.80 0.36 0.66
Carcinoma 433,099 Disease Target CA 72-4 184 66 0.01 -0.80 0.36 0.60
BMP-14 14 Target Target BMP-2 3,889 5 0.02 -0.80 0.36 0.70
Epiregulin 291 Target Target beta-Cellulin 17 6 0.09 -0.80 0.35 0.80
CCL5 2,002 Target Target CCL3 1,427 500 0.30 -0.70 0.35 0.89
Cancer 1,053,491 Disease Target BRSK1 20 7 0.00 -0.81 0.35 0.56
Cyclooxygenase-3 20 Target Target Cox-2 21,583 7 0.01 -0.81 0.35 0.66
Hearing Loss 30,622 Disease Target ACTG1 41 14 0.01 -0.81 0.34 0.66
Cancer 1,053,491 Disease Target Equilibrative Nucleoside Transporter 1 211 71 0.00 -0.81 0.34 0.58
CCL5 2,002 Target Target CCL2 3,560 673 0.25 -0.73 0.34 0.87
Lung Cancer 91,416 Disease Target Alk Tyrosine Kinase Receptor 3 1 0.00 -0.82 0.33 0.60
Non Small Cell Lung Cancer 28,563 Disease Target Alk Tyrosine Kinase Receptor 3 1 0.00 -0.82 0.33 0.63
Carcinoma 433,099 Disease Target Heat Shock Protein Hsp 90-Beta 3 1 0.00 -0.82 0.33 0.57
Mu Opioid Receptor 4,576 Target Target CTAP-3 6 2 0.01 -0.82 0.33 0.68
Calmodulin 25,240 Target Target Tubulin Beta-1 Chain 3 1 0.00 -0.82 0.33 0.63
BMP-2B 18 Target Target Collagen 138,882 6 0.00 -0.82 0.33 0.61
BMP-2B 18 Target Target BMP-4 1,255 6 0.04 -0.81 0.33 0.74
Kadsulignan L 3 Drug Target Platelet Activating Factor 9,915 1 0.01 -0.82 0.33 0.65
Shock 134,031 Disease Target Tubulin Beta-1 Chain 3 1 0.00 -0.82 0.33 0.59
Dpdpe 1,204 Drug Target CTAP-3 6 2 0.02 -0.82 0.33 0.72
Atacand (Candesartan Cilexetil)- FDA 3 Drug Target Renin 43,456 1 0.00 -0.82 0.33 0.62
CCL3 1,427 Target Target CXCL4/PF4 9 3 0.03 -0.82 0.33 0.72
Tubulin Beta-1 Chain 3 Target Target Inosine-5'-Monophosphate Dehydrogenase 261 1 0.04 -0.81 0.33 0.76
CXCL11 526 Target Target CXCL4/PF4 9 3 0.04 -0.81 0.33 0.76
Cancer 1,053,491 Disease Target CHK1 2,044 681 0.01 -0.82 0.33 0.60
Cancer 1,053,491 Disease Target AKT2 873 284 0.01 -0.82 0.33 0.59
CCL2 3,560 Target Target CXCL10/IP-10 114 37 0.06 -0.82 0.32 0.75
CXCL10/IP-10 114 Target Target CXCL9 1,016 37 0.11 -0.81 0.32 0.81
Obesity 138,233 Disease Target Adiponectin 11,994 3,886 0.10 -0.81 0.32 0.72
BMP-4 1,255 Target Target BMP-2 3,889 399 0.18 -0.78 0.32 0.83
Infection 766,637 Disease Target CRG-2 41 13 0.00 -0.83 0.32 0.57
Ovarian Cancer 33,996 Disease Target Kallikrein-8 19 6 0.01 -0.83 0.32 0.64
CD4 112,219 Target Target CD154 1,512 477 0.04 -0.83 0.32 0.67
Cancer 1,053,491 Disease Target Glutathione S-Transferase Theta-1 70 22 0.00 -0.83 0.31 0.57
EPHB2 385 Target Target EPHB1 137 43 0.19 -0.78 0.31 0.86
Cancer 1,053,491 Disease Target Epiregulin 291 91 0.01 -0.83 0.31 0.58
BD2 76 Target Target BD3 32 10 0.20 -0.77 0.31 0.88
Arixtra (Fondaparinux Sodium)- FDA 16 Drug Target Bivalirudin 891 5 0.04 -0.83 0.31 0.75
CCL7 274 Target Target CCL8 197 60 0.26 -0.74 0.30 0.90
BMP-7 1,112 Target Target BMP-2 3,889 338 0.16 -0.80 0.30 0.82
Niemann Pick Disease 1,234 Disease Target Sphingomyelinase 3,060 369 0.19 -0.79 0.30 0.84
CCN5 57 Target Target CYR61 539 17 0.10 -0.82 0.30 0.81
Cancer 1,053,491 Disease Target BRK 236 70 0.00 -0.84 0.30 0.57
Epidermal Growth Factor Receptor 24,772 Target Target Epigen 27 8 0.01 -0.84 0.30 0.65
Epigen 27 Target Target Epiregulin 291 8 0.09 -0.83 0.30 0.81
Cancer 1,053,491 Disease Target Urokinase-Type Plasminogen Activator 3,939 1,166 0.02 -0.84 0.30 0.60
Epidermal Growth Factor Receptor 24,772 Target Target beta-Cellulin 17 5 0.01 -0.84 0.29 0.65
Endostatin 1,599 Target Target Angiostatin K1-3 17 5 0.03 -0.84 0.29 0.73
Cancer 1,053,491 Disease Target CAPG 85 25 0.00 -0.84 0.29 0.57
Cancer 1,053,491 Disease Target beta-Cellulin 17 5 0.00 -0.84 0.29 0.56
Diabetes 332,602 Disease Target Adiponectin 11,994 3,433 0.05 -0.84 0.29 0.66
Carcinoma 433,099 Disease Target AP2M1 7 2 0.00 -0.85 0.29 0.57
Cancer 1,053,491 Disease Target AP2M1 7 2 0.00 -0.85 0.29 0.56
Cancer 1,053,491 Disease Target EPHB4 329 94 0.01 -0.85 0.29 0.58
Cancer 1,053,491 Disease Target CXCL14/BRAK 7 2 0.00 -0.85 0.29 0.56
CD31/PECAM1 7 Target Target CD34 24,598 2 0.00 -0.85 0.29 0.64
Abciximab (ReoPro)- FDA 7 Drug Target Eptifibatide 772 2 0.03 -0.84 0.29 0.73
Leukemia 162,805 Disease Target Cardiotrophin-1 351 100 0.01 -0.85 0.28 0.63
AACT 109 Target Target Alpha-1 AntiChymotrypsin 1,460 31 0.08 -0.84 0.28 0.78
Cancer 1,053,491 Disease Target CCN5 57 16 0.00 -0.85 0.28 0.56
Cancer 1,053,491 Disease Target Ret Proto-Oncogene 1,005 281 0.01 -0.85 0.28 0.58
Cancer 1,053,491 Disease Target Hypoxia-Inducible Factor 1-Alpha 923 257 0.01 -0.85 0.28 0.58
Aldosterone Receptor 528 Target Target Renin 43,456 147 0.03 -0.85 0.28 0.68
Des (1-3) IGF-I 191 Target Target Des (1-6) IGF-II 18 5 0.09 -0.84 0.28 0.81
Angiotensin Converting Enzyme 31,674 Target Target Aldosterone Receptor 528 146 0.04 -0.85 0.28 0.69
Cancer 1,053,491 Disease Target Cytokeratin 8 587 162 0.01 -0.85 0.28 0.58
Epidermal Growth Factor Receptor 24,772 Target Target Epiregulin 291 80 0.03 -0.85 0.27 0.69
Cancer 1,053,491 Disease Target ERBB4 994 273 0.01 -0.85 0.27 0.58
Diabetes 332,602 Disease Target ADSF 11 3 0.00 -0.85 0.27 0.58
ADSF 11 Target Target Adiponectin 11,994 3 0.01 -0.85 0.27 0.66
Cholesterol 182,390 Disease Target APOC1 126 34 0.01 -0.85 0.27 0.61
CD4 112,219 Target Target 4-1BB Ligand 135 36 0.01 -0.86 0.27 0.63