PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
Cancer 1,053,491 Disease Target Collapsin Response Mediator Protein-1 30 8 0.00 -0.86 0.27 0.56
Cancer 1,053,491 Disease Target Glutathione S-Transferase A3 15 4 0.00 -0.86 0.27 0.56
BMX 185 Target Target BTK 1,263 49 0.10 -0.84 0.26 0.80
CXCL10 2,386 Target Target CCL8 197 52 0.08 -0.85 0.26 0.77
Mu Opioid Receptor 4,576 Target Target Mu-Type Opioid Receptor 19 5 0.02 -0.86 0.26 0.69
CCL2 3,560 Target Target CXCL3 145 38 0.05 -0.85 0.26 0.75
BMP-6 386 Target Target BMP-4 1,255 101 0.15 -0.82 0.26 0.83
Infection 766,637 Disease Target Toll-Like Receptor 2 2,174 568 0.01 -0.86 0.26 0.60
Cancer 1,053,491 Disease Target ACVR1B 23 6 0.00 -0.86 0.26 0.56
Cancer 1,053,491 Disease Target AXL 633 165 0.01 -0.86 0.26 0.58
CD146 729 Target Target CD34 24,598 190 0.04 -0.86 0.26 0.71
ELC 355 Target Target Exodus-2 27 7 0.07 -0.85 0.26 0.79
Exodus-2 27 Target Target CCL21 808 7 0.05 -0.86 0.26 0.76
Calmodulin 25,240 Target Target DAPK2 27 7 0.01 -0.86 0.26 0.65
Acute Coronary Syndromes 9,133 Disease Target Eptifibatide 772 200 0.08 -0.85 0.26 0.75
CD148 74 Target Target DEP-1 88 19 0.24 -0.76 0.26 0.90
Cancer 1,053,491 Disease Target CYR61 539 138 0.01 -0.86 0.26 0.58
CCL2 3,560 Target Target CXCL2 750 192 0.12 -0.84 0.26 0.80
CD4 112,219 Target Target CD137 474 120 0.02 -0.86 0.25 0.64
Cancer 1,053,491 Disease Target EPHB2 385 97 0.00 -0.86 0.25 0.57
Platelet Aggregation 25,460 Disease Target Eptifibatide 772 194 0.04 -0.86 0.25 0.71
Epidermal Growth Factor Receptor 24,772 Target Target ERBB3 1,154 289 0.05 -0.86 0.25 0.72
Infection 766,637 Disease Target CXCL9 1,016 254 0.01 -0.87 0.25 0.59
CCL2 3,560 Target Target CCL1 220 55 0.06 -0.86 0.25 0.76
Cancer 1,053,491 Disease Target 4-1BB Receptor 20 5 0.00 -0.87 0.25 0.56
Colon Cancer 30,064 Disease Target Prostaglandin Reductase 1 8 2 0.00 -0.87 0.25 0.63
Shock 134,031 Disease Target Glutathione S-Transferase Mu 2 8 2 0.00 -0.87 0.25 0.60
Carcinoma 433,099 Disease Target Aldo-Keto Reductase Family 1 Member C3 8 2 0.00 -0.87 0.25 0.57
Ck-beta-11 4 Target Target Exodus-3 8 1 0.18 -0.81 0.25 0.89
Ck-beta-11 4 Target Target Exodus-2 27 1 0.10 -0.85 0.25 0.84
Kappa-Type Opioid Receptor 4 Target Target Sphingosine 1-Phosphate Receptor 1 150 1 0.04 -0.86 0.25 0.77
Estrogen Receptor Beta 1,924 Target Target Egl Nine Homolog 1 4 1 0.01 -0.87 0.25 0.69
Acarbose (Precose)- FDA 4 Drug Target Alpha-Glucosidase 4,319 1 0.01 -0.87 0.25 0.67
CCL4 5,638 Target Target CCBL1 4 1 0.01 -0.87 0.25 0.66
Major Depressive Disorder 12,517 Disease Target Melatonin Receptor Type 1a 4 1 0.00 -0.87 0.25 0.64
Alprostadil for Injection (Edex)- FDA 4 Drug Target Antithrombin 13,773 1 0.00 -0.87 0.25 0.64
Acetaminophen and Codeine (Tylenol-Codeine)- FDA 4 Drug Target Cox-2 21,583 1 0.00 -0.87 0.25 0.63
Ck-beta-11 4 Target Target CD34 24,598 1 0.00 -0.87 0.25 0.63
Epidermal Growth Factor Receptor 24,772 Target Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.63
Xaa-Pro Dipeptidase 4 Target Target EGF 27,487 1 0.00 -0.87 0.25 0.62
Cervical Cancer 28,286 Disease Target Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 1 0.00 -0.87 0.25 0.62
Infectious Diseases 33,605 Disease Target CCBL1 4 1 0.00 -0.87 0.25 0.62
Meningitis 41,685 Disease Target CCBL1 4 1 0.00 -0.87 0.25 0.62
Prostate Cancer 71,064 Disease Target Egl Nine Homolog 1 4 1 0.00 -0.87 0.25 0.60
Shock 134,031 Disease Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.59
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 Target Target Collagen 138,882 1 0.00 -0.87 0.25 0.59
Stroke 146,992 Disease Target E-Selectin/CD62E 4 1 0.00 -0.87 0.25 0.59
Stroke 146,992 Disease Target Melatonin Receptor Type 1a 4 1 0.00 -0.87 0.25 0.59
Depression 220,092 Disease Target Melatonin Receptor Type 1a 4 1 0.00 -0.87 0.25 0.58
Diabetes 332,602 Disease Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.57
Diabetes 332,602 Disease Target E-Selectin/CD62E 4 1 0.00 -0.87 0.25 0.57
Carcinoma 433,099 Disease Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.57
Carcinoma 433,099 Disease Target Egl Nine Homolog 1 4 1 0.00 -0.87 0.25 0.57
Carcinoma 433,099 Disease Target CCBL1 4 1 0.00 -0.87 0.25 0.57
Infection 766,637 Disease Target CCBL1 4 1 0.00 -0.87 0.25 0.56
Cancer 1,053,491 Disease Target Ck-beta-11 4 1 0.00 -0.87 0.25 0.55
Cancer 1,053,491 Disease Target Xaa-Pro Dipeptidase 4 1 0.00 -0.87 0.25 0.55
Cancer 1,053,491 Disease Target Egl Nine Homolog 1 4 1 0.00 -0.87 0.25 0.55
Cancer 1,053,491 Disease Target Melatonin Receptor Type 1a 4 1 0.00 -0.87 0.25 0.55
Cancer 1,053,491 Disease Target CCBL1 4 1 0.00 -0.87 0.25 0.55
BMP-6 386 Target Target BMP-7 1,112 95 0.15 -0.83 0.25 0.84
4-1BB Ligand 135 Target Target CD137 474 33 0.13 -0.84 0.24 0.84
Diabetes 332,602 Disease Target Glucagon Receptor 537 131 0.01 -0.87 0.24 0.61
Carcinoma 433,099 Disease Target Cytokeratin 8 587 143 0.01 -0.87 0.24 0.60
Infection 766,637 Disease Target CXCL10 2,386 580 0.01 -0.87 0.24 0.60
Carcinoma 433,099 Disease Target CA 15-3 898 217 0.01 -0.87 0.24 0.60
Cancer 1,053,491 Disease Target Glutathione Peroxidase 2 67 16 0.00 -0.87 0.24 0.56
Infection 766,637 Disease Target Protein Fimh 21 5 0.00 -0.87 0.24 0.56
Infection 766,637 Disease Target CCL3 1,427 339 0.01 -0.87 0.24 0.59
Infection 766,637 Disease Target CXCL2 750 178 0.01 -0.87 0.24 0.59
CXCL10/IP-10 114 Target Target CXCL11 526 27 0.11 -0.85 0.24 0.82
CCL5 2,002 Target Target CXCL10/IP-10 114 27 0.06 -0.87 0.24 0.76
Infection 766,637 Disease Target CCL5 2,002 472 0.01 -0.87 0.24 0.59
Carcinoma 433,099 Disease Target CEA 17,022 4,013 0.05 -0.87 0.24 0.65
Cancer 1,053,491 Disease Target DNA-damage-inducible transcript 3 30 7 0.00 -0.88 0.23 0.56
Cancer 1,053,491 Disease Target Cox-2 21,583 5,031 0.03 -0.87 0.23 0.61
CCL5 2,002 Target Target CXCL10 2,386 464 0.21 -0.79 0.23 0.87
Alpha (Prolastin)- FDA 13 Drug Target Elastase 13,875 3 0.01 -0.88 0.23 0.65
Obesity 138,233 Disease Target Acetyl-Coa Carboxylase 1 118 27 0.01 -0.88 0.23 0.62
CCL5 2,002 Target Target CCL8 197 45 0.07 -0.87 0.23 0.78
Breast Cancer 173,695 Disease Target CCN5 57 13 0.00 -0.88 0.23 0.60
Ovarian Cancer 33,996 Disease Target Kallikrein-6 79 18 0.01 -0.88 0.23 0.65
Cancer 1,053,491 Disease Target BMPR1A 279 63 0.00 -0.88 0.23 0.57
Cancer 1,053,491 Disease Target Cytokeratin 18 1,108 249 0.01 -0.88 0.22 0.58
DAPK2 27 Target Target DAPK1 205 6 0.08 -0.87 0.22 0.81
Cancer 1,053,491 Disease Target DAPK2 27 6 0.00 -0.88 0.22 0.56
Allopurinol (Zyloprim)- FDA 18 Drug Target Xanthine Oxidase 8,860 4 0.01 -0.88 0.22 0.67
CXCL9 1,016 Target Target CXCL4/PF4 9 2 0.02 -0.88 0.22 0.72
BAFF 1,240 Target Target CD254 9 2 0.02 -0.88 0.22 0.72
CCL2 3,560 Target Target CXCL4/PF4 9 2 0.01 -0.88 0.22 0.68
Cancer 1,053,491 Disease Target CXCL4/PF4 9 2 0.00 -0.88 0.22 0.55
Cancer 1,053,491 Disease Target CD254 9 2 0.00 -0.88 0.22 0.55
CCL2 3,560 Target Target CXCL10 2,386 530 0.18 -0.81 0.22 0.85
CCL7 274 Target Target CCL5 2,002 60 0.08 -0.87 0.22 0.79
Infection 766,637 Disease Target CCL8 197 43 0.00 -0.88 0.22 0.57
Angiotensin Converting Enzyme 31,674 Target Target Renin 43,456 6,899 0.19 -0.81 0.22 0.81
EGF 27,487 Target Target ERBB3 1,154 251 0.04 -0.88 0.22 0.71
ACVR1B 23 Target Target Activin A 2,048 5 0.02 -0.88 0.22 0.72
Cancer 1,053,491 Disease Target Multidrug Resistance-Associated Protein 2 462 100 0.00 -0.89 0.22 0.57
Antithrombin 13,773 Target Target D-Dimer 6,185 1,337 0.14 -0.84 0.22 0.81