PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Exodus-2 27 Target Target Exodus-3 8 7 0.48 -0.30 0.88 0.92
Abacavir Sulfate (Ziagen)- FDA 61 Drug Drug Abacavir 1,496 53 0.18 -0.36 0.87 0.81
Actonel (Risedronate Sodium)- FDA 7 Drug Drug Alendronate Sodium (Fosamax)- FDA 38 6 0.37 -0.35 0.86 0.90
Cancer 1,053,491 Disease Drug Aromasin (Exemestane)- FDA 7 6 0.00 -0.38 0.86 0.58
Aromasin (Exemestane)- FDA 7 Drug Disease Breast Cancer 173,695 6 0.01 -0.38 0.86 0.62
Nephropathy Diabetic 13 Disease Disease Diabetic Nephropathy 12,496 11 0.03 -0.39 0.85 0.69
Amitiza (Lubiprostone)- FDA 19 Drug Disease Constipation 15,810 16 0.03 -0.40 0.84 0.69
ACAT2 145 Target Disease Cholesterol 182,390 122 0.02 -0.40 0.84 0.65
Schizophrenia 77,034 Disease Disease Schizoaffective Disorder 3,104 2,592 0.17 -0.40 0.84 0.75
Stroke 146,992 Disease Drug Alteplase (Activase)- FDA 112 92 0.02 -0.42 0.82 0.65
Stroke 146,992 Disease Drug Activase (Alteplase)- FDA 112 92 0.02 -0.42 0.82 0.65
Adefovir Dipivoxil (Hepsera)- FDA 22 Drug Disease Hepatitis B 57,815 18 0.02 -0.43 0.82 0.65
Adefovir Dipivoxil (Hepsera)- FDA 22 Drug Disease Hepatitis 163,842 18 0.01 -0.43 0.82 0.63
Rheumatoid Arthritis 78,952 Disease Disease Arthritis Juvenile 27 22 0.02 -0.43 0.81 0.65
D(1a) Dopamine Receptor 51 Target Target D(2) Dopamine Receptor 1,559 41 0.15 -0.44 0.80 0.80
CD4 112,219 Target Target CCL27/CTACK 5 4 0.01 -0.45 0.80 0.62
Kadsurenone 70 Drug Target Platelet Activating Factor 9,915 56 0.07 -0.45 0.80 0.73
Cancer 1,053,491 Disease Drug Abarelix (Plenaxis)- FDA 5 4 0.00 -0.45 0.80 0.57
Nausea 42,627 Disease Drug Aloxi (Palonosetron hydrochloride)- FDA 10 8 0.01 -0.45 0.80 0.65
Prostate Cancer 71,064 Disease Drug Abarelix (Plenaxis)- FDA 5 4 0.01 -0.45 0.80 0.63
Asparaginase (Elspar)- FDA 10 Drug Disease Leukemia 162,805 8 0.01 -0.45 0.80 0.62
Anakinra (Kineret)- FDA 10 Drug Disease Arthritis 128,324 8 0.01 -0.45 0.80 0.62
Anakinra (Kineret)- FDA 10 Drug Disease Rheumatoid Arthritis 78,952 8 0.01 -0.45 0.80 0.64
Glaucoma 41,465 Disease Disease Hypertension Ocular 5 4 0.01 -0.45 0.80 0.65
Doxazolidine 9 Drug Drug Doxorubicin 28,033 7 0.01 -0.47 0.78 0.66
Cancer 1,053,491 Disease Target CA 15-3 898 698 0.02 -0.47 0.78 0.61
Cancer 1,053,491 Disease Drug Doxifluridine 267 206 0.01 -0.48 0.77 0.60
Diabetes 332,602 Disease Target CAMK1D 21 16 0.01 -0.49 0.76 0.61
BAFF 1,240 Target Target BAFFR 44 33 0.14 -0.49 0.75 0.80
Cancer 1,053,491 Disease Target Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 4 3 0.00 -0.50 0.75 0.57
Cancer 1,053,491 Disease Target Aldo-Keto Reductase Family 1 Member C3 8 6 0.00 -0.50 0.75 0.58
ELC 355 Target Target Ck-beta-11 4 3 0.08 -0.50 0.75 0.78
Obesity 138,233 Disease Drug Adipex-P (Phentermine Hydrochloride)- FDA 36 27 0.01 -0.50 0.75 0.63
Leukemia 162,805 Disease Drug Arranon (Nelarabine)- FDA 12 9 0.01 -0.50 0.75 0.62
Accolate (Zafirlukast)- FDA 4 Drug Disease Asthma 109,610 3 0.00 -0.50 0.75 0.62
Carcinoma Basal Cell 8 Disease Disease Basal Cell Carcinoma 7,953 6 0.02 -0.50 0.75 0.69
Cancer 1,053,491 Disease Drug Abarelix 51 38 0.01 -0.50 0.75 0.59
Prostate Cancer 71,064 Disease Drug Abarelix 51 38 0.02 -0.50 0.75 0.66
Amitiza (Lubiprostone)- FDA 19 Drug Drug Alprostadil (Prostin VR Pediatric)- FDA 26 14 0.63 -0.35 0.74 0.96
Amitiza (Lubiprostone)- FDA 19 Drug Disease Irritable Bowel Syndrome 8,230 14 0.04 -0.51 0.74 0.71
ApoE4 1,525 Target Target APOE 12,771 1,119 0.25 -0.49 0.73 0.82
Diabetes 332,602 Disease Disease Neuropathy Diabetic 15 11 0.00 -0.52 0.73 0.60
Mu Opioid Receptor 4,576 Target Target Opioid Receptor Mu 71 51 0.09 -0.53 0.72 0.76
Alitretinoin (Panretin)- FDA 7 Drug Drug Aquasol A (Vitamin A)- FDA 46 5 0.28 -0.50 0.71 0.88
Cancer 1,053,491 Disease Drug Alimta (Pemetrexed)- FDA 28 20 0.00 -0.53 0.71 0.58
Arava (Leflunomide)- FDA 14 Drug Disease Arthritis 128,324 10 0.01 -0.53 0.71 0.63
Actonel (Risedronate Sodium)- FDA 7 Drug Disease Osteoporosis 46,215 5 0.01 -0.53 0.71 0.64
ACRP30 102 Target Target Adiponectin 11,994 72 0.07 -0.54 0.71 0.73
EGF 27,487 Target Target beta-Cellulin 17 12 0.02 -0.54 0.71 0.67
CXCL11 526 Target Target CXCL10 2,386 369 0.33 -0.50 0.70 0.87
Cancer 1,053,491 Disease Drug Axitinib (Inlyta)- FDA 10 7 0.00 -0.55 0.70 0.57
Breast Cancer 173,695 Disease Drug Anastrozole (Arimidex)- FDA 10 7 0.01 -0.55 0.70 0.61
Arimidex (Anastrozole)- FDA 10 Drug Disease Breast Cancer 173,695 7 0.01 -0.55 0.70 0.61
Calmodulin 25,240 Target Target CAMK4 43 30 0.03 -0.55 0.70 0.69
CD14 9,941 Target Target Endotoxin receptor 115 80 0.07 -0.55 0.70 0.74
Avastin (Bevacizumab)- FDA 207 Drug Disease Cancer 1,053,491 144 0.01 -0.55 0.70 0.60
Alpha-Amylase 7,171 Target Target AMY1A 13 9 0.03 -0.55 0.69 0.70
CA125 Antigen 78 Target Disease Cancer 1,053,491 54 0.01 -0.55 0.69 0.59
Diabetes 332,602 Disease Disease Nephropathy Diabetic 13 9 0.00 -0.55 0.69 0.60
Acitretin (Soriatane)- FDA 13 Drug Disease Psoriasis 26,882 9 0.02 -0.55 0.69 0.66
Osteoporosis 46,215 Disease Drug Alendronate Sodium (Fosamax)- FDA 38 26 0.02 -0.56 0.68 0.66
Kaad-Cyclopamine 19 Drug Disease Cancer 1,053,491 13 0.00 -0.56 0.68 0.58
Ns3 3,189 Target Disease Hepatitis 163,842 2,173 0.10 -0.56 0.68 0.71
Cholesterol 182,390 Disease Target Squalene Monooxygenase 28 19 0.01 -0.57 0.68 0.62
ApoE2 517 Target Target ApoE4 1,525 348 0.39 -0.50 0.67 0.89
Schizophrenia 77,034 Disease Disease Schizotypal Personality Disorder 497 334 0.05 -0.57 0.67 0.69
Depression 220,092 Disease Disease Major Depressive Disorder 12,517 8,352 0.16 -0.57 0.67 0.73
N-Heptanoyl-L-Homoserine Lactone 3 Drug Target C7 7,027 2 0.01 -0.58 0.67 0.68
Analgesia 44,857 Disease Drug Acular (Ketorolac Tromethamine)- FDA 6 4 0.01 -0.58 0.67 0.64
Almotriptan Malate (Axert)- FDA 5 Drug Drug Amerge (Naratriptan)- FDA 3 2 0.52 -0.45 0.67 0.95
Cancer 1,053,491 Disease Drug Dromostanolone Propionate 3 2 0.00 -0.58 0.67 0.57
Cancer 1,053,491 Disease Drug Aminoglutethimide (Cytadren)- FDA 3 2 0.00 -0.58 0.67 0.57
Xanthine Oxidase 8,860 Target Drug Anturane (Sulfinpyrazone)- FDA 3 2 0.01 -0.58 0.67 0.67
Gout 8,355 Disease Drug Anturane (Sulfinpyrazone)- FDA 3 2 0.01 -0.58 0.67 0.68
Headache 50,687 Disease Drug Agrylin (Anagrelide)- FDA 3 2 0.01 -0.58 0.67 0.63
Migraine 24,200 Disease Drug Amerge (Naratriptan)- FDA 3 2 0.01 -0.58 0.67 0.65
Pain 409,851 Disease Drug Agrylin (Anagrelide)- FDA 3 2 0.00 -0.58 0.67 0.59
Axert (Almotriptan Malate)- FDA 5 Drug Drug Amerge (Naratriptan)- FDA 3 2 0.52 -0.45 0.67 0.95
Doxpicomine 3 Drug Disease Pain 409,851 2 0.00 -0.58 0.67 0.59
Acyclovir for Injection (Zovirax Injection)- FDA 3 Drug Disease Retinitis 9,116 2 0.01 -0.58 0.67 0.67
Cancer 1,053,491 Disease Disease Carcinoma Renal 6 4 0.00 -0.58 0.67 0.57
Anagrelide (Agrylin)- FDA 3 Drug Disease Headache 50,687 2 0.01 -0.58 0.67 0.63
Anagrelide (Agrylin)- FDA 3 Drug Disease Pain 409,851 2 0.00 -0.58 0.67 0.59
Dromostanolone Propionate 3 Drug Disease Breast Cancer 173,695 2 0.00 -0.58 0.67 0.60
Aminoglutethimide (Cytadren)- FDA 3 Drug Disease Breast Cancer 173,695 2 0.00 -0.58 0.67 0.60
CXCL9 1,016 Target Target CXCL10 2,386 676 0.43 -0.49 0.67 0.90
Kaempferitrin 32 Drug Drug Kaempferol 2,992 21 0.07 -0.58 0.66 0.75
APOE 12,771 Target Target APOC1 126 82 0.06 -0.59 0.65 0.73
Lung Cancer 91,416 Disease Drug Alimta (Pemetrexed)- FDA 28 18 0.01 -0.60 0.64 0.64
Arava (Leflunomide)- FDA 14 Drug Disease Rheumatoid Arthritis 78,952 9 0.01 -0.60 0.64 0.63
Alimta (Pemetrexed)- FDA 28 Drug Disease Lung Cancer 91,416 18 0.01 -0.60 0.64 0.64
Multiple Myeloma 24,594 Disease Disease Myeloma Multiple 11 7 0.01 -0.60 0.64 0.66
Fracture 111,575 Disease Drug Alendronate Sodium (Fosamax)- FDA 38 24 0.01 -0.61 0.63 0.64
Actos (Pioglitazone Hydrochloride)- FDA 38 Drug Drug Avandia (Rosiglitazone Maleate)- FDA 66 24 0.48 -0.48 0.63 0.94
Acamprosate Calcium (Campral)- FDA 30 Drug Drug Antabuse (Disulfiram)- FDA 27 17 0.60 -0.40 0.63 0.96
ELC 355 Target Target Exodus-3 8 5 0.09 -0.61 0.62 0.79
Carcinoma Basal Cell 8 Disease Disease Cancer 1,053,491 5 0.00 -0.61 0.62 0.57
Cancer 1,053,491 Disease Target Erbb2 4,536 2,833 0.04 -0.61 0.62 0.63
CA 15-3 898 Target Disease Breast Cancer 173,695 557 0.04 -0.62 0.62 0.67
ATAC 239 Target Disease Cancer 1,053,491 148 0.01 -0.62 0.62 0.59