PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Maternal Embryonic Leucine Zipper Kinase 39 Target Target CCNB1 160 1 0.01 -0.98 0.03 0.74
CD68 6,424 Target Target Alpha-1 AntiChymotrypsin 1,460 39 0.01 -0.98 0.03 0.69
APOE 12,771 Target Target Alpha-1 AntiChymotrypsin 1,460 55 0.01 -0.98 0.04 0.67
BRSK1 20 Target Disease Menopause 19,680 8 0.01 -0.77 0.40 0.66
ERK1 18,374 Target Target BDNF 11,163 183 0.01 -0.99 0.02 0.66
Alpha-2c Adrenergic Receptor 42 Target Target Alpha-1b Adrenergic Receptor 145 1 0.01 -0.98 0.02 0.75
BMP-4 1,255 Target Target BRK 236 7 0.01 -0.98 0.03 0.71
CD68 6,424 Target Target Collagen 138,882 385 0.01 -0.97 0.06 0.62
CD22 1,591 Target Target BLyS 457 11 0.01 -0.98 0.02 0.71
EDF 379 Target Disease Urticaria 10,717 26 0.01 -0.96 0.07 0.67
Hiv-1 Integrase 1,199 Target Drug Kadsurarin 5 1 0.01 -0.89 0.20 0.70
ERK1 18,374 Target Target Collagen 138,882 654 0.01 -0.98 0.04 0.62
CA125 Antigen 78 Target Target BD2 76 1 0.01 -0.99 0.01 0.76
CD154 1,512 Target Target CD95 4,266 33 0.01 -0.99 0.02 0.70
CCL19 658 Target Target CXCL4/PF4 9 1 0.01 -0.94 0.11 0.71
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target C1orf41 1 1 0.01 -0.71 1.00 0.68
Myeloperoxidase 16,181 Target Disease Sepsis 64,798 421 0.01 -0.98 0.03 0.63
Antithrombin 13,773 Target Disease Acute Coronary Syndromes 9,133 146 0.01 -0.99 0.02 0.67
Angiotensin Converting Enzyme 31,674 Target Disease Cholesterol 182,390 990 0.01 -0.98 0.03 0.61
C7 7,027 Target Disease Pain 409,851 704 0.01 -0.95 0.10 0.60
ApoE2 517 Target Disease Hyperlipidemia 15,317 37 0.01 -0.96 0.07 0.67
C5a 4,164 Target Target Elastase 13,875 100 0.01 -0.98 0.02 0.67
CD68 6,424 Target Target CCL2 3,560 63 0.01 -0.99 0.02 0.69
CD4 112,219 Target Target CCL21 808 126 0.01 -0.92 0.16 0.63
Sodium Channel Nav1.8 31 Target Target Artemin 184 1 0.01 -0.98 0.03 0.74
EGF 27,487 Target Disease Glioblastoma 17,933 294 0.01 -0.99 0.02 0.66
Endostatin 1,599 Target Disease Cancer 1,053,491 544 0.01 -0.81 0.34 0.59
CD4 112,219 Target Disease Infectious Diseases 33,605 815 0.01 -0.98 0.02 0.62
CD4 112,219 Target Target CCL5 2,002 199 0.01 -0.95 0.10 0.63
Erbb2 4,536 Target Target Prostaglandin E2 Receptor Ep4 Subtype 5 2 0.01 -0.77 0.40 0.69
Adiponectin 11,994 Target Disease Hyperlipidemia 15,317 181 0.01 -0.99 0.02 0.67
CCL19 658 Target Target CCL14 34 2 0.01 -0.97 0.06 0.72
BLK 255 Target Target ETS1 539 5 0.01 -0.99 0.02 0.73
BMP-6 386 Target Target Activin A 2,048 12 0.01 -0.98 0.03 0.71
CD4 112,219 Target Disease Leishmaniasis 15,049 556 0.01 -0.98 0.04 0.62
Collagen 138,882 Target Target EGF 27,487 836 0.01 -0.98 0.03 0.62
CD4 112,219 Target Disease Inflammatory Bowel Disease 24,375 709 0.01 -0.98 0.03 0.62
Epidermal Growth Factor Receptor 24,772 Target Target Cox-2 21,583 314 0.01 -0.99 0.01 0.66
Macrophage Metalloelastase 100 Target Target Elastase 13,875 16 0.01 -0.92 0.16 0.67
Eotaxin 2,457 Target Target CCL1 220 10 0.01 -0.98 0.05 0.70
CXCL11 526 Target Target CRG-2 41 2 0.01 -0.97 0.05 0.73
Collagen 138,882 Target Target CD34 24,598 798 0.01 -0.98 0.03 0.62
Aldosterone Receptor 528 Target Disease Gynecomastia 2,594 16 0.01 -0.98 0.03 0.70
CCL19 658 Target Target Exodus-3 8 1 0.01 -0.93 0.12 0.72
Histamine H1 Receptor 1,170 Target Disease Urticaria 10,717 49 0.01 -0.98 0.04 0.68
CCL7 274 Target Target Eotaxin-2/CCL24 19 1 0.01 -0.97 0.05 0.73
ApoE2 517 Target Disease Hypertriglyceridemia 7,877 28 0.01 -0.97 0.05 0.68
CD14 9,941 Target Target CCL2 3,560 83 0.01 -0.98 0.02 0.68
C7 7,027 Target Disease Scoliosis 14,102 139 0.01 -0.99 0.02 0.67
Eotaxin-3/CCL26 26 Target Target CCL8 197 1 0.01 -0.98 0.04 0.74
Calmodulin 25,240 Target Target Beta-Tubulin 4,870 155 0.01 -0.98 0.03 0.66
Collagen 138,882 Target Target Elastase 13,875 616 0.01 -0.98 0.04 0.62
Epidermal Growth Factor Receptor 24,772 Target Disease Colon Cancer 30,064 383 0.01 -0.99 0.02 0.66
CCL4 5,638 Target Target Collagen 138,882 393 0.01 -0.96 0.07 0.63
CD4 112,219 Target Disease Retinitis 9,116 450 0.01 -0.97 0.05 0.63
AKT2 873 Target Target Erbb2 4,536 28 0.01 -0.98 0.03 0.70
CD14 9,941 Target Target CD146 729 38 0.01 -0.97 0.05 0.68
Myeloperoxidase 16,181 Target Target C5a 4,164 116 0.01 -0.98 0.03 0.67
BMP-2B 18 Target Target BMP-7 1,112 2 0.01 -0.94 0.11 0.71
APOA1 958 Target Disease Dyslipidemia 15,225 54 0.01 -0.97 0.06 0.67
CCL14 34 Target Target CXCL3 145 1 0.01 -0.98 0.03 0.75
Androgen Receptor 12,918 Target Disease Gynecomastia 2,594 83 0.01 -0.98 0.03 0.68
Myeloperoxidase 16,181 Target Target Cox-2 21,583 268 0.01 -0.99 0.02 0.67
APOE 12,771 Target Disease Dyslipidemia 15,225 200 0.01 -0.99 0.02 0.67
APOH 110 Target Target APOE 12,771 17 0.01 -0.92 0.15 0.67
Myeloperoxidase 16,181 Target Disease Inflammatory Bowel Diseases 4,684 125 0.01 -0.98 0.03 0.67
CCL14 34 Target Target CCL2 3,560 5 0.01 -0.92 0.15 0.69
Carbonic Anhydrase 4 9 Target Target ADRP 537 1 0.01 -0.94 0.11 0.72
Estrogen Receptor Beta 1,924 Target Disease Breast Cancer 173,695 263 0.01 -0.93 0.14 0.63
Erbb2 4,536 Target Target BRAF 4,766 67 0.01 -0.99 0.01 0.70
Bile Salt Export Pump 476 Target Target Multidrug Resistance Protein 1 495 7 0.01 -0.99 0.01 0.74
ACTG1 41 Target Target CALR 117 1 0.01 -0.98 0.02 0.76
Platelet Activating Factor 9,915 Target Disease Asthma 109,610 476 0.01 -0.97 0.05 0.63
Carbonic Anhydrase 3 36 Target Target Glutathione Peroxidase 3 132 1 0.01 -0.98 0.03 0.75
CD4 112,219 Target Disease Asthma 109,610 1,614 0.01 -0.99 0.01 0.62
CD4 112,219 Target Disease Influenza 67,933 1,279 0.01 -0.98 0.02 0.62
BD3 32 Target Target CXCL3 145 1 0.01 -0.98 0.03 0.75
CD14 9,941 Target Disease Infection 766,637 1,283 0.01 -0.93 0.13 0.59
CD4 112,219 Target Target CXCL9 1,016 159 0.01 -0.92 0.16 0.64
Epidermal Growth Factor Receptor 24,772 Target Disease Lung Carcinoma 13,423 272 0.01 -0.98 0.02 0.66
CA 72-4 184 Target Target AFP 9,751 20 0.01 -0.94 0.11 0.68
CD22 1,591 Target Target BAFF 1,240 21 0.01 -0.98 0.02 0.72
CCL14 34 Target Target CXCL11 526 2 0.01 -0.97 0.06 0.73
Alpha-Glucosidase 4,319 Target Drug Alglucosidase Alfa (Myozyme)- FDA 4 2 0.02 -0.71 0.50 0.69
Alpha-Glucosidase 4,319 Target Drug Alglucosidase Alfa (Lumizyme)- FDA 1 1 0.02 -0.71 1.00 0.69
CXCL16 341 Target Target CCL21 808 8 0.02 -0.98 0.02 0.73
Methylenetetrahydrofolate Reductase 3,573 Target Target Antithrombin 13,773 107 0.02 -0.98 0.03 0.68
CD137 474 Target Target CD254 9 1 0.02 -0.94 0.11 0.72
Alcohol Dehydrogenase 8,492 Target Drug Antizol (Fomepizole)- FDA 2 2 0.02 -0.58 1.00 0.68
bFGF 9,327 Target Target BDNF 11,163 157 0.02 -0.98 0.02 0.69
APOE 12,771 Target Disease Inflammation 252,734 876 0.02 -0.96 0.07 0.61
CXCL7 76 Target Target CCL1 220 2 0.02 -0.98 0.03 0.75
Eotaxin-2/CCL24 19 Target Target CCL1 220 1 0.02 -0.97 0.05 0.74
Eotaxin 2,457 Target Disease Allergic Rhinitis 12,280 85 0.02 -0.98 0.03 0.68
CD22 1,591 Target Target Ricin 3,034 34 0.02 -0.98 0.02 0.71
CCNB1 160 Target Target AURKC 26 1 0.02 -0.98 0.04 0.75
CD4 112,219 Target Disease Hepatitis B 57,815 1,254 0.02 -0.98 0.02 0.62
BLyS 457 Target Target CD254 9 1 0.02 -0.94 0.11 0.73
DDR2 194 Target Target BRAF 4,766 15 0.02 -0.96 0.08 0.70
Cysteinyl Leukotriene Receptor 2 24 Target Target Arachidonate 5-Lipoxygenase 170 1 0.02 -0.98 0.04 0.75