PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
CAMK2A 42 Target Target CAMK2B 21 2 0.07 -0.93 0.10 0.83
EPHA4 357 Target Target EPHB2 385 25 0.07 -0.93 0.07 0.82
BD2 76 Target Target BD4 26 3 0.07 -0.92 0.12 0.82
Alpha-Glucosidase 4,319 Target Target Alpha-Amylase 7,171 376 0.07 -0.93 0.09 0.77
CNTF 1,613 Target Target Cardiotrophin-1 351 51 0.07 -0.91 0.15 0.78
CNTF 1,613 Target Target BDNF 11,163 292 0.07 -0.89 0.18 0.75
CCL7 274 Target Target CCL1 220 17 0.07 -0.93 0.08 0.82
CCL3 1,427 Target Target CCL1 220 39 0.07 -0.89 0.18 0.78
APOE 12,771 Target Disease Cholesterol 182,390 3,396 0.07 -0.85 0.27 0.69
ELC 355 Target Target Exodus-2 27 7 0.07 -0.85 0.26 0.79
CCL5 2,002 Target Target CCL8 197 45 0.07 -0.87 0.23 0.78
CCL3 1,427 Target Target CCL8 197 38 0.07 -0.89 0.19 0.78
Epidermal Growth Factor Receptor 24,772 Target Target Erbb2 4,536 770 0.07 -0.90 0.17 0.74
C5a 4,164 Target Target C4A 1,177 161 0.07 -0.91 0.14 0.78
CCL5 2,002 Target Target CXCL11 526 75 0.07 -0.91 0.14 0.79
CCL14 34 Target Target CCL8 197 6 0.07 -0.89 0.18 0.81
APOA1 958 Target Target APOA2 118 25 0.07 -0.88 0.21 0.79
Cytokeratin 8 587 Target Target Cytokeratin 18 1,108 60 0.07 -0.92 0.10 0.81
CD14 9,941 Target Target Endotoxin receptor 115 80 0.07 -0.55 0.70 0.74
CCL7 274 Target Target CXCL2 750 34 0.08 -0.91 0.12 0.81
CXCL10 2,386 Target Target CCL8 197 52 0.08 -0.85 0.26 0.77
AACT 109 Target Target Alpha-1 AntiChymotrypsin 1,460 31 0.08 -0.84 0.28 0.78
Alpha-2a Adrenergic Receptor 188 Target Target Alpha-2c Adrenergic Receptor 42 7 0.08 -0.90 0.17 0.82
Epidermal Growth Factor Receptor 24,772 Target Disease Lung Cancer 91,416 3,773 0.08 -0.90 0.15 0.72
Epidermal Growth Factor Receptor 24,772 Target Disease Lung Cancer 91,416 3,773 0.08 -0.90 0.15 0.72
ELC 355 Target Target Ck-beta-11 4 3 0.08 -0.50 0.75 0.78
EPHA4 357 Target Target EPHA3 140 18 0.08 -0.91 0.13 0.82
DAPK2 27 Target Target DAPK1 205 6 0.08 -0.87 0.22 0.81
CCL7 274 Target Target CCL5 2,002 60 0.08 -0.87 0.22 0.79
CCL7 274 Target Target CCL3 1,427 51 0.08 -0.89 0.19 0.79
CA 72-4 184 Target Target CA 15-3 898 34 0.08 -0.89 0.18 0.80
Epidermal Growth Factor Receptor 24,772 Target Disease Cancer 1,053,491 13,587 0.08 -0.67 0.55 0.66
Des (1-3) IGF-I 191 Target Target Des (1-6) IGF-II 18 5 0.09 -0.84 0.28 0.81
Epiregulin 291 Target Target beta-Cellulin 17 6 0.09 -0.80 0.35 0.80
CXCL7 76 Target Target CXCL3 145 9 0.09 -0.91 0.12 0.84
CD1A 2,739 Target Target CD14 9,941 456 0.09 -0.89 0.17 0.77
Mu Opioid Receptor 4,576 Target Drug Dpdpe 1,204 206 0.09 -0.89 0.17 0.79
Eotaxin 2,457 Target Target Eotaxin-2/CCL24 19 19 0.09 -0.22 1.00 0.76
CKMM 55 Target Target CKBB 57 5 0.09 -0.91 0.09 0.86
Mu Opioid Receptor 4,576 Target Target Opioid Receptor Mu 71 51 0.09 -0.53 0.72 0.76
Epigen 27 Target Target Epiregulin 291 8 0.09 -0.83 0.30 0.81
FABP3 134 Target Target FABP1 90 10 0.09 -0.91 0.11 0.84
EPHB4 329 Target Target EPHB3 118 18 0.09 -0.90 0.15 0.82
ELC 355 Target Target Exodus-3 8 5 0.09 -0.61 0.62 0.79
CCL4 5,638 Target Target CCL5 2,002 316 0.09 -0.89 0.16 0.79
Ns3 3,189 Target Disease Hepatitis 163,842 2,173 0.10 -0.56 0.68 0.71
EPHB4 329 Target Target EPHB2 385 34 0.10 -0.90 0.10 0.84
Ck-beta-11 4 Target Target Exodus-2 27 1 0.10 -0.85 0.25 0.84
CCN5 57 Target Target CYR61 539 17 0.10 -0.82 0.30 0.81
CXCL9 1,016 Target Target CCL3 1,427 117 0.10 -0.90 0.12 0.82
Ent2 108 Target Target Equilibrative Nucleoside Transporter 1 211 15 0.10 -0.89 0.14 0.84
CCL2 3,560 Target Target CXCL9 1,016 190 0.10 -0.88 0.19 0.80
BMX 185 Target Target BTK 1,263 49 0.10 -0.84 0.26 0.80
Eotaxin 2,457 Target Target Eotaxin-3/CCL26 26 26 0.10 -0.19 1.00 0.77
BD3 32 Target Target BD4 26 3 0.10 -0.90 0.12 0.86
CD4 112,219 Target Disease Infection 766,637 30,996 0.11 -0.83 0.28 0.68
Epidermal Growth Factor Receptor 24,772 Target Disease Non Small Cell Lung Cancer 28,563 2,827 0.11 -0.89 0.11 0.78
CXCL10/IP-10 114 Target Target CXCL9 1,016 37 0.11 -0.81 0.32 0.81
CD1A 2,739 Target Target CD68 6,424 458 0.11 -0.88 0.17 0.80
CCL2 3,560 Target Target CCL8 197 92 0.11 -0.72 0.47 0.78
Dihydropteroate Synthase 408 Target Target Dihydrofolate Reductase 5,563 166 0.11 -0.76 0.41 0.78
CXCL10/IP-10 114 Target Target CXCL11 526 27 0.11 -0.85 0.24 0.82
CRG-2 41 Target Target CRG-10 2 1 0.11 -0.70 0.50 0.83
CEA 17,022 Target Target CA 15-3 898 437 0.11 -0.71 0.49 0.76
CCL2 3,560 Target Target CXCL2 750 192 0.12 -0.84 0.26 0.80
CCL3 1,427 Target Target CXCL2 750 123 0.12 -0.87 0.16 0.83
CCL18 256 Target Target DC-CK1 22 9 0.12 -0.76 0.41 0.82
AMY2B 21 Target Target AMY1A 13 2 0.12 -0.87 0.15 0.87
Bile Salt Export Pump 476 Target Target Multidrug Resistance-Associated Protein 2 462 57 0.12 -0.88 0.12 0.85
CXCL10/IP-10 114 Target Target CXCL4/PF4 9 4 0.12 -0.73 0.44 0.83
CCL5 2,002 Target Target CXCL9 1,016 180 0.13 -0.87 0.18 0.83
Artemin 184 Target Target Enovin 3 3 0.13 -0.50 1.00 0.81
CCL3 1,427 Target Target CXCL10 2,386 238 0.13 -0.87 0.17 0.83
4-1BB Ligand 135 Target Target CD137 474 33 0.13 -0.84 0.24 0.84
BMP-6 386 Target Target BMP-2 3,889 163 0.13 -0.74 0.42 0.80
EPHB3 118 Target Target EPHB1 137 17 0.13 -0.87 0.14 0.87
Tissue-Type Plasminogen Activator 5,020 Target Target Urokinase-Type Plasminogen Activator 3,939 603 0.14 -0.86 0.15 0.83
Androgen Receptor 12,918 Target Disease Prostate Cancer 71,064 4,112 0.14 -0.80 0.32 0.76
BAFF 1,240 Target Target BAFFR 44 33 0.14 -0.49 0.75 0.80
BMP-7 1,112 Target Target BMP-4 1,255 169 0.14 -0.86 0.15 0.85
Antithrombin 13,773 Target Target D-Dimer 6,185 1,337 0.14 -0.84 0.22 0.81
Angiotensin Converting Enzyme 31,674 Target Target Angiotensin-Converting Enzyme 2 665 665 0.14 -0.04 1.00 0.76
BMP-6 386 Target Target BMP-7 1,112 95 0.15 -0.83 0.25 0.84
BMP-6 386 Target Target BMP-4 1,255 101 0.15 -0.82 0.26 0.83
D(1a) Dopamine Receptor 51 Target Target D(2) Dopamine Receptor 1,559 41 0.15 -0.44 0.80 0.80
bFGF 9,327 Target Target aFGF 899 448 0.15 -0.69 0.50 0.79
Alpha-Glucosidase 4,319 Target Target Lysosomal Alpha-Glucosidase 105 105 0.16 -0.10 1.00 0.79
BMP-7 1,112 Target Target BMP-2 3,889 338 0.16 -0.80 0.30 0.82
CCL7 274 Target Target CCL2 3,560 164 0.17 -0.62 0.60 0.81
4-1BB Receptor 20 Target Target 4-1BB Ligand 135 9 0.17 -0.72 0.45 0.85
ApoE2 517 Target Target APOE 12,771 454 0.18 -0.34 0.88 0.78
Ck-beta-11 4 Target Target Exodus-3 8 1 0.18 -0.81 0.25 0.89
Epidermal Growth Factor Receptor 24,772 Target Target EGF 27,487 4,679 0.18 -0.82 0.19 0.82
BMP-4 1,255 Target Target BMP-2 3,889 399 0.18 -0.78 0.32 0.83
CCL2 3,560 Target Target CXCL10 2,386 530 0.18 -0.81 0.22 0.85
Angiotensin Converting Enzyme 31,674 Target Target Renin 43,456 6,899 0.19 -0.81 0.22 0.81
EPHB2 385 Target Target EPHB1 137 43 0.19 -0.78 0.31 0.86
CCL4 5,638 Target Target CCL3 1,427 535 0.19 -0.75 0.37 0.83
AMAC-1 19 Target Target DC-CK1 22 4 0.20 -0.80 0.21 0.90
BD2 76 Target Target BD3 32 10 0.20 -0.77 0.31 0.88