PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
CD4 112,219 Target Disease Carcinoma 433,099 1,988 0.01 -0.99 0.02 0.56
Collagenase-3 367 Target Disease Osteoarthritis 36,287 33 0.01 -0.95 0.09 0.64
ACRP30 102 Target Disease Obesity 138,233 34 0.01 -0.82 0.33 0.62
ENO2 87 Target Target EPHA3 140 1 0.01 -0.99 0.01 0.74
C5a 4,164 Target Target Eotaxin 2,457 29 0.01 -0.99 0.01 0.68
Glucocorticoid Receptor 10,306 Target Disease Inflammation 252,734 464 0.01 -0.98 0.05 0.59
Angiotensin Converting Enzyme 31,674 Target Disease Glomerulonephritis 23,459 248 0.01 -0.99 0.01 0.63
Epidermal Growth Factor Receptor 24,772 Target Disease Prostate Cancer 71,064 382 0.01 -0.99 0.02 0.61
CCL7 274 Target Target DNAJB1 44 1 0.01 -0.99 0.02 0.72
CCL18 256 Target Target CXCL2 750 4 0.01 -0.99 0.02 0.71
Endoglin 1,333 Target Target CD254 9 1 0.01 -0.94 0.11 0.69
BMP-6 386 Target Target BMPR1A 279 3 0.01 -0.99 0.01 0.72
Angiotensin Converting Enzyme 31,674 Target Disease Kidney Diseases 4,651 111 0.01 -0.99 0.02 0.64
Angiotensin Converting Enzyme 31,674 Target Disease Hyperlipidemia 15,317 202 0.01 -0.99 0.01 0.63
CD68 6,424 Target Disease Arthritis 128,324 264 0.01 -0.98 0.04 0.61
CD4 112,219 Target Disease Diarrhea 51,986 705 0.01 -0.99 0.01 0.60
D-Dimer 6,185 Target Disease Sepsis 64,798 185 0.01 -0.98 0.03 0.62
APOH 110 Target Target APOA1 958 3 0.01 -0.98 0.03 0.70
CD4 112,219 Target Target 4-1BB Ligand 135 36 0.01 -0.86 0.27 0.63
CD4 112,219 Target Disease Malaria 56,215 735 0.01 -0.99 0.01 0.60
CEA 17,022 Target Disease Ovarian Cancer 33,996 223 0.01 -0.99 0.01 0.63
DC-CK1 22 Target Target CXCL11 526 1 0.01 -0.98 0.05 0.71
BLyS 457 Target Disease Rheumatoid Arthritis 78,952 56 0.01 -0.94 0.12 0.63
AACT 109 Target Target APOE 12,771 11 0.01 -0.95 0.10 0.66
Adenosine Deaminase 6,613 Target Disease Leukemia 162,805 306 0.01 -0.98 0.05 0.61
ATAC 239 Target Disease Cancer 1,053,491 148 0.01 -0.62 0.62 0.59
Androgen Receptor 12,918 Target Target Aldo-Keto Reductase Family 1 Member C3 8 3 0.01 -0.79 0.38 0.66
Chorionic Gonadotropin beta 936 Target Disease Down Syndrome 10,290 29 0.01 -0.98 0.03 0.66
APOE 12,771 Target Disease Heart Disease 118,291 364 0.01 -0.98 0.03 0.61
Multidrug Resistance-Associated Protein 2 462 Target Disease Breast Cancer 173,695 84 0.01 -0.90 0.18 0.62
CAMK2D 21 Target Target CYR61 539 1 0.01 -0.97 0.05 0.71
CD1A 2,739 Target Target CCL21 808 14 0.01 -0.99 0.02 0.69
Eotaxin 2,457 Target Target CXCL10/IP-10 114 5 0.01 -0.98 0.04 0.69
AGP 2,006 Target Disease Inflammation 252,734 214 0.01 -0.94 0.11 0.60
BD2 76 Target Target CXCL3 145 1 0.01 -0.99 0.01 0.74
Catechol O-Methyltransferase 2,877 Target Disease Attention Deficit Hyperactivity Disorder 14,687 62 0.01 -0.99 0.02 0.66
CCL19 658 Target Target Sphingosine 1-Phosphate Receptor 1 150 3 0.01 -0.99 0.02 0.71
Angiotensin Converting Enzyme 31,674 Target Disease Inflammation 252,734 859 0.01 -0.98 0.03 0.59
CD4 112,219 Target Disease Organ Transplantation 11,384 344 0.01 -0.98 0.03 0.61
Aurora B kinase 415 Target Target AURKC 26 1 0.01 -0.98 0.04 0.72
CD14 9,941 Target Target CCL5 2,002 43 0.01 -0.99 0.02 0.67
Cytokeratin 20 847 Target Disease Cancer 1,053,491 288 0.01 -0.81 0.34 0.59
CAMK2A 42 Target Target CCL18 256 1 0.01 -0.99 0.02 0.73
CCL4 5,638 Target Disease Liver Disease 49,817 163 0.01 -0.98 0.03 0.63
Calmodulin 25,240 Target Target Glutamate Receptor 1 352 29 0.01 -0.96 0.08 0.65
APOA2 118 Target Target APOE 12,771 12 0.01 -0.95 0.10 0.66
Myeloperoxidase 16,181 Target Target CD14 9,941 124 0.01 -0.99 0.01 0.65
Epidermal Growth Factor Receptor 24,772 Target Target Epigen 27 8 0.01 -0.84 0.30 0.65
CD95 4,266 Target Disease Leukemia 162,805 258 0.01 -0.97 0.06 0.61
BAFF 1,240 Target Disease Rheumatoid Arthritis 78,952 97 0.01 -0.96 0.08 0.63
Cox-2 21,583 Target Disease Lung Cancer 91,416 436 0.01 -0.99 0.02 0.61
Renin 43,456 Target Disease Inflammation 252,734 1,029 0.01 -0.99 0.02 0.58
Renin 43,456 Target Target 11-Beta-Hydroxylase 721 55 0.01 -0.96 0.08 0.64
Angiotensin Converting Enzyme 31,674 Target Target BNP 6,842 145 0.01 -0.99 0.02 0.64
Collagen 138,882 Target Target Platelet Activating Factor 9,915 366 0.01 -0.98 0.04 0.61
Angiotensin Converting Enzyme 31,674 Target Disease Acute Coronary Syndromes 9,133 168 0.01 -0.99 0.02 0.64
CXCL16 341 Target Target CXCL2 750 5 0.01 -0.99 0.01 0.72
ApoE4 1,525 Target Disease Hyperlipoproteinemia 2,954 21 0.01 -0.99 0.01 0.69
Annexin A1 406 Target Target Glutathione S-Transferase A2 25 1 0.01 -0.98 0.04 0.72
Steroid 5-Alpha-Reductase 293 Target Disease Baldness 865 5 0.01 -0.99 0.02 0.71
ERK1 18,374 Target Target Epiregulin 291 23 0.01 -0.96 0.08 0.66
CD4 112,219 Target Disease Psoriasis 26,882 547 0.01 -0.99 0.02 0.61
CCL19 658 Target Target CXCL2 750 7 0.01 -0.99 0.01 0.72
CD14 9,941 Target Disease Shock 134,031 364 0.01 -0.98 0.04 0.61
CCL5 2,002 Target Target Small Inducible Cytokine A2 5 1 0.01 -0.89 0.20 0.69
CXCL7 76 Target Target CXCL11 526 2 0.01 -0.98 0.03 0.72
ERK1 18,374 Target Target bFGF 9,327 131 0.01 -0.99 0.01 0.65
CXCL4/PF4 9 Target Target Cytokeratin 18 1,108 1 0.01 -0.94 0.11 0.70
CAMK2A 42 Target Disease Cerebrovascular Disorder 237 1 0.01 -0.99 0.02 0.73
CD4 112,219 Target Target CCL3 1,427 127 0.01 -0.95 0.09 0.62
ASK1 762 Target Target Glutathione Peroxidase 6 13 1 0.01 -0.96 0.08 0.70
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target Glutathione S-Transferase A3 15 3 0.01 -0.89 0.20 0.67
Glutathione S-Transferase A1 111 Target Target Udp-Glucuronosyltransferase 2,219 5 0.01 -0.98 0.05 0.69
Beta-Glucosidase 4,297 Target Target Alpha-Amylase 7,171 56 0.01 -0.99 0.01 0.67
Angiotensin Converting Enzyme 31,674 Target Disease Non Insulin Dependent Diabetes Mellitus 6,686 147 0.01 -0.99 0.02 0.64
Phospholipase A2 13,400 Target Disease Cholesterol 182,390 500 0.01 -0.98 0.04 0.60
EPHA3 140 Target Target BMPR1A 279 2 0.01 -0.99 0.01 0.73
Collagen 138,882 Target Disease Proteinuria 28,803 641 0.01 -0.99 0.02 0.60
Glutathione Peroxidase 2 67 Target Target CXCL3 145 1 0.01 -0.99 0.01 0.74
FABP3 134 Target Target ANGPTL4 289 2 0.01 -0.99 0.01 0.73
CCL7 274 Target Disease Inflammation 252,734 85 0.01 -0.83 0.31 0.62
CD4 112,219 Target Disease Sarcoidosis 19,176 474 0.01 -0.99 0.02 0.61
EPHB1 137 Target Target BMPR1A 279 2 0.01 -0.99 0.01 0.73
Androgen Receptor 12,918 Target Disease Infertility 35,448 219 0.01 -0.99 0.02 0.64
C5a 4,164 Target Disease Adult Respiratory Distress Syndrome 4,034 42 0.01 -0.99 0.01 0.69
Cathepsin G 1,613 Target Disease Inflammation 252,734 207 0.01 -0.93 0.13 0.61
Vanilloid Receptor 1 404 Target Disease Pain 409,851 132 0.01 -0.82 0.33 0.61
ERK1 18,374 Target Target BRAF 4,766 96 0.01 -0.99 0.02 0.65
CD68 6,424 Target Target Elastase 13,875 97 0.01 -0.99 0.02 0.66
CD4 112,219 Target Target Eotaxin 2,457 171 0.01 -0.96 0.07 0.62
Calmodulin 25,240 Target Target ERK1 18,374 222 0.01 -0.99 0.01 0.65
CXCL11 526 Target Disease Inflammation 252,734 119 0.01 -0.88 0.23 0.61
CD68 6,424 Target Disease Rheumatoid Arthritis 78,952 234 0.01 -0.98 0.04 0.62
CA 72-4 184 Target Disease Ovarian Cancer 33,996 26 0.01 -0.93 0.14 0.65
Glutathione S-Transferase Theta-1 70 Target Target Glutathione Peroxidase 3 132 1 0.01 -0.99 0.01 0.74
CCL4 5,638 Target Disease Inflammation 252,734 393 0.01 -0.96 0.07 0.60
Myeloperoxidase 16,181 Target Disease Hemorrhage 100,979 421 0.01 -0.98 0.03 0.61
Dihydrofolate Reductase 5,563 Target Disease Leukemia 162,805 314 0.01 -0.97 0.06 0.61
Myeloperoxidase 16,181 Target Disease Leukemias 14,152 158 0.01 -0.99 0.01 0.66
Angiostatin K1-3 17 Target Target ETS1 539 1 0.01 -0.97 0.06 0.71