PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Word 1
Word 1 Count
CAT1
CAT2
Word 2
Word 2 Count
Co-occurrence
Occurence-Centile
Correlation
Overlap-Metric
G-Metric
Aurora B kinase 415 Target Target Aurora Kinase A 196 3 0.01 -0.99 0.02 0.73
CRG-2 41 Target Target CCL1 220 1 0.01 -0.99 0.02 0.73
Angiotensin Converting Enzyme 31,674 Target Target Collagen 138,882 699 0.01 -0.99 0.02 0.60
BMPR1A 279 Target Target BMP-2 3,889 11 0.01 -0.98 0.04 0.69
Histamine H1 Receptor 1,170 Target Drug Doxantrazole 122 4 0.01 -0.98 0.03 0.71
Angiotensin Converting Enzyme 31,674 Target Disease Nephrotic Syndrome 14,681 229 0.01 -0.99 0.02 0.64
APOE 12,771 Target Target BCHE 1,167 41 0.01 -0.98 0.04 0.66
CXCL16 341 Target Target Eotaxin-3/CCL26 26 1 0.01 -0.98 0.04 0.72
AFP 9,751 Target Target Cytokeratin 18 1,108 35 0.01 -0.98 0.03 0.67
DAPK1 205 Target Target CAMK4 43 1 0.01 -0.99 0.02 0.73
Cyclooxygenase-3 20 Target Target Cox-2 21,583 7 0.01 -0.81 0.35 0.66
ADRP 537 Target Target Inosine-5'-Monophosphate Dehydrogenase 261 4 0.01 -0.99 0.02 0.72
APOA1 958 Target Disease Hyperlipidemia 15,317 41 0.01 -0.98 0.04 0.66
Antithrombin 13,773 Target Disease Nephrotic Syndrome 14,681 153 0.01 -0.99 0.01 0.66
Eotaxin 2,457 Target Target CXCL9 1,016 17 0.01 -0.99 0.02 0.70
Chorionic Gonadotropin beta 936 Target Disease Testicular Cancer 4,459 22 0.01 -0.99 0.02 0.69
Androgen Receptor 12,918 Target Disease Baldness 865 36 0.01 -0.98 0.04 0.66
CAMK2A 42 Target Target DAPK1 205 1 0.01 -0.99 0.02 0.73
Erbb2 4,536 Target Target beta-Cellulin 17 3 0.01 -0.91 0.18 0.68
CCL18 256 Target Target CCL4 5,638 13 0.01 -0.97 0.05 0.68
Angiotensin Converting Enzyme 31,674 Target Disease Dyslipidemia 15,225 238 0.01 -0.99 0.02 0.64
ERK1 18,374 Target Target Insulin-Like Growth Factor 1 Receptor 1,052 48 0.01 -0.98 0.05 0.66
DMPK 609 Target Target Metabotropic Glutamate Receptor 3 55 2 0.01 -0.98 0.04 0.72
EGF 27,487 Target Disease Lung Cancer 91,416 549 0.01 -0.99 0.02 0.62
Toll-Like Receptor 2 2,174 Target Target CXCL2 750 14 0.01 -0.99 0.02 0.70
Myeloperoxidase 16,181 Target Target Platelet Activating Factor 9,915 139 0.01 -0.99 0.01 0.66
Glyceraldehyde 3-Phosphate Dehydrogenase 5,919 Target Target Beta-Tubulin 4,870 59 0.01 -0.99 0.01 0.68
BAFF 1,240 Target Target CCL21 808 11 0.01 -0.99 0.01 0.71
CCL18 256 Target Target CCL21 808 5 0.01 -0.99 0.02 0.72
EPHB3 118 Target Target BMPR1A 279 2 0.01 -0.99 0.02 0.73
D-Dimer 6,185 Target Disease Inflammation 252,734 437 0.01 -0.96 0.07 0.60
Epidermal Growth Factor Receptor 24,772 Target Disease Ovarian Cancer 33,996 321 0.01 -0.99 0.01 0.64
ERK1 18,374 Target Target ERBB3 1,154 51 0.01 -0.98 0.04 0.66
Ns3 3,189 Target Disease Liver Disease 49,817 140 0.01 -0.98 0.04 0.64
Myeloperoxidase 16,181 Target Disease Shock 134,031 519 0.01 -0.98 0.03 0.61
CCL2 3,560 Target Target CXCL4/PF4 9 2 0.01 -0.88 0.22 0.68
Endoglin 1,333 Target Target CD34 24,598 64 0.01 -0.97 0.05 0.65
FABP3 134 Target Target ADRP 537 3 0.01 -0.99 0.02 0.72
Glucocorticoid Receptor 10,306 Target Disease Shock 134,031 416 0.01 -0.98 0.04 0.61
Glutathione Peroxidase 2 67 Target Target Glutathione Synthetase 471 2 0.01 -0.98 0.03 0.72
CCL7 274 Target Target CXCL10/IP-10 114 2 0.01 -0.99 0.02 0.74
Epigen 27 Target Target ERBB3 1,154 2 0.01 -0.96 0.07 0.70
BMP-2B 18 Target Target BMP-2 3,889 3 0.01 -0.91 0.17 0.68
Cytokeratin 20 847 Target Target Cytokeratin 18 1,108 11 0.01 -0.99 0.01 0.72
Epidermal Growth Factor Receptor 24,772 Target Disease Diarrhea 51,986 408 0.01 -0.99 0.02 0.63
Estrogen Receptor Beta 1,924 Target Target Egl Nine Homolog 1 4 1 0.01 -0.87 0.25 0.69
CD22 1,591 Target Target CD1A 2,739 24 0.01 -0.99 0.02 0.70
CCL14 34 Target Target CCL1 220 1 0.01 -0.98 0.03 0.73
CD254 9 Target Target CCL21 808 1 0.01 -0.94 0.11 0.71
CD4 112,219 Target Disease Cryptococcosis 3,853 244 0.01 -0.97 0.06 0.62
ERK1 18,374 Target Disease Breast Cancer 173,695 665 0.01 -0.98 0.04 0.61
ACTG1 41 Target Target AHSG 176 1 0.01 -0.98 0.02 0.74
Myeloperoxidase 16,181 Target Target CD34 24,598 235 0.01 -0.99 0.01 0.65
ANXA7 35 Target Target DAPK1 205 1 0.01 -0.98 0.03 0.74
Annexin A1 406 Target Target Galectin-1 1,131 8 0.01 -0.99 0.02 0.71
CCL7 274 Target Target Eotaxin-3/CCL26 26 1 0.01 -0.98 0.04 0.73
CCL1 220 Target Target CCL21 808 5 0.01 -0.99 0.02 0.72
CCL19 658 Target Target CD4 112,219 102 0.01 -0.92 0.16 0.63
Neuropeptide S Receptor 77 Target Disease Panic Disorder 7,455 9 0.01 -0.94 0.12 0.68
Cox-2 21,583 Target Disease Ulcers 45,142 371 0.01 -0.99 0.02 0.64
bFGF 9,327 Target Target Activin A 2,048 52 0.01 -0.98 0.03 0.68
Aldosterone Receptor 528 Target Disease Ventricular Dysfunction 12,856 31 0.01 -0.97 0.06 0.67
Bile Salt Export Pump 476 Target Disease Liver Disease 49,817 58 0.01 -0.94 0.12 0.64
CD1A 2,739 Target Target CCL19 658 16 0.01 -0.98 0.02 0.70
bFGF 9,327 Target Target BMP-2 3,889 72 0.01 -0.99 0.02 0.68
Maternal Embryonic Leucine Zipper Kinase 39 Target Disease Glioblastoma 17,933 10 0.01 -0.86 0.26 0.66
BMP-2B 18 Target Target BMP-6 386 1 0.01 -0.97 0.06 0.72
COP-1 118 Target Disease Relapsing Remitting Multiple Sclerosis 2,115 6 0.01 -0.97 0.05 0.70
CKMM 55 Target Target APOC1 126 1 0.01 -0.99 0.02 0.75
Alpha-2a Adrenergic Receptor 188 Target Disease Attention Deficit Hyperactivity Disorder 14,687 20 0.01 -0.94 0.11 0.67
Estrogen Receptor Beta 1,924 Target Disease Cancer 1,053,491 543 0.01 -0.85 0.28 0.59
CCL14 34 Target Target CCL21 808 2 0.01 -0.97 0.06 0.71
Mu Opioid Receptor 4,576 Target Target CTAP-3 6 2 0.01 -0.82 0.33 0.68
Alpha-Glucosidase 4,319 Target Disease Muscle Weakness 9,178 76 0.01 -0.99 0.02 0.68
BNP 6,842 Target Target BNP/NPPB 1 1 0.01 -0.71 1.00 0.68
Catechol O-Methyltransferase 2,877 Target Disease Dyskinesia 9,738 64 0.01 -0.99 0.02 0.68
Alpha-2a Adrenergic Receptor 188 Target Target Alpha-1b Adrenergic Receptor 145 2 0.01 -0.99 0.01 0.75
Erbb2 4,536 Target Target ERK1 18,374 111 0.01 -0.98 0.02 0.66
Buserelin 1,249 Target Disease Infertility 35,448 81 0.01 -0.97 0.06 0.65
C5a 4,164 Target Disease Sepsis 64,798 200 0.01 -0.97 0.05 0.64
Erbb2 4,536 Target Target Epiregulin 291 14 0.01 -0.97 0.05 0.69
COP-1 118 Target Target CCN5 57 1 0.01 -0.99 0.02 0.75
CD22 1,591 Target Target CD68 6,424 39 0.01 -0.98 0.02 0.68
CCL18 256 Target Target Eotaxin-3/CCL26 26 1 0.01 -0.98 0.04 0.73
Xanthine Oxidase 8,860 Target Drug Anturane (Sulfinpyrazone)- FDA 3 2 0.01 -0.58 0.67 0.67
Calmodulin 25,240 Target Target Phospholipase A2 13,400 227 0.01 -0.99 0.02 0.65
Urokinase-Type Plasminogen Activator 3,939 Target Disease Breast Cancer 173,695 323 0.01 -0.96 0.08 0.62
Calmodulin 25,240 Target Target CAMK2B 21 9 0.01 -0.76 0.43 0.66
Androgen Receptor 12,918 Target Disease Carcinoma 433,099 928 0.01 -0.96 0.07 0.59
CCL21 808 Target Target Exodus-3 8 1 0.01 -0.93 0.12 0.71
Steroid 5-Alpha-Reductase 293 Target Target Steroid Delta-Isomerase 22 1 0.01 -0.98 0.05 0.73
CCL19 658 Target Target CCL4 5,638 24 0.01 -0.98 0.04 0.69
CCL4 5,638 Target Target CXCL10/IP-10 114 10 0.01 -0.95 0.09 0.68
ANGPTL4 289 Target Target Peroxisome Proliferator-Activated Receptor Delta 355 4 0.01 -0.99 0.01 0.74
CCL14 34 Target Target CXCL2 750 2 0.01 -0.97 0.06 0.72
Androgen Receptor 12,918 Target Disease Breast Cancer 173,695 596 0.01 -0.97 0.05 0.61
BMP-7 1,112 Target Target Activin A 2,048 19 0.01 -0.99 0.02 0.71
ANGPT2 105 Target Target CYR61 539 3 0.01 -0.98 0.03 0.73
ENO2 87 Target Target ANGPTL4 289 2 0.01 -0.99 0.02 0.74
CNTF 1,613 Target Disease Amyotrophic Lateral Sclerosis 14,006 60 0.01 -0.98 0.04 0.67