PHARMA - Relationships

Relationships Table

Entities - Color - Target Drug Disease Lo Med Hi
Aurora B kinase 415 Target Target Aurora A kinase 318 14 0.04 -0.96 0.04 0.79
CD1A 2,739 Target Target CD34 24,598 317 0.04 -0.93 0.12 0.71
ERK1 18,374 Target Target EGF 27,487 878 0.04 -0.96 0.05 0.71
Analgesia 44,857 Disease Target Mu Opioid Receptor 4,576 567 0.04 -0.93 0.12 0.70
BMP-2B 18 Target Target BMP-4 1,255 6 0.04 -0.81 0.33 0.74
CXCL10 2,386 Target Target CCL1 220 29 0.04 -0.93 0.13 0.75
ERBB4 994 Target Target EGF 27,487 210 0.04 -0.88 0.21 0.70
C5a 4,164 Target Target Platelet Activating Factor 9,915 259 0.04 -0.96 0.06 0.73
Kappa-Type Opioid Receptor 4 Target Target Sphingosine 1-Phosphate Receptor 1 150 1 0.04 -0.86 0.25 0.77
CCL5 2,002 Target Target CXCL3 145 22 0.04 -0.92 0.15 0.75
Diabetic Nephropathy 12,496 Disease Target Renin 43,456 953 0.04 -0.95 0.08 0.70
Cancer 1,053,491 Disease Target Erbb2 4,536 2,833 0.04 -0.61 0.62 0.63
4-1BB Receptor 20 Target Target CD137 474 4 0.04 -0.89 0.20 0.76
Alpha-Glucosidase 4,319 Target Target Pancreatic Alpha-Amylase 423 56 0.04 -0.93 0.13 0.74
CCL19 658 Target Target CXCL9 1,016 34 0.04 -0.96 0.05 0.78
CD4 112,219 Target Target CD14 9,941 1,398 0.04 -0.92 0.14 0.68
Arixtra (Fondaparinux Sodium)- FDA 16 Drug Target Bivalirudin 891 5 0.04 -0.83 0.31 0.75
Tissue-Type Plasminogen Activator 5,020 Target Target D-Dimer 6,185 235 0.04 -0.96 0.05 0.75
BAFFR 44 Target Target BLyS 457 6 0.04 -0.92 0.14 0.77
CXCL9 1,016 Target Target CXCL2 750 37 0.04 -0.96 0.05 0.78
Arthritis 128,324 Disease Target Collagen 138,882 5,668 0.04 -0.96 0.04 0.68
Bivalirudin 891 Target Target Eptifibatide 772 36 0.04 -0.96 0.05 0.79
CD68 6,424 Target Target CD34 24,598 546 0.04 -0.95 0.08 0.72
CXCL11 526 Target Target CXCL3 145 12 0.04 -0.95 0.08 0.78
CXCL11 526 Target Target CXCL4/PF4 9 3 0.04 -0.81 0.33 0.76
Platelet Aggregation 25,460 Disease Target Eptifibatide 772 194 0.04 -0.86 0.25 0.71
CD14 9,941 Target Target Toll-Like Receptor 2 2,174 204 0.04 -0.94 0.09 0.73
CXCL16 341 Target Target CXCL9 1,016 26 0.04 -0.95 0.08 0.77
EPHA2 532 Target Target EPHB1 137 12 0.04 -0.94 0.09 0.78
EGF 27,487 Target Target ERBB3 1,154 251 0.04 -0.88 0.22 0.71
CCL18 256 Target Target CCL3 1,427 27 0.04 -0.94 0.11 0.76
Myeloperoxidase 16,181 Target Target Elastase 13,875 671 0.04 -0.96 0.05 0.74
CD146 729 Target Target CD34 24,598 190 0.04 -0.86 0.26 0.71
CCL4 5,638 Target Target CXCL10 2,386 165 0.04 -0.95 0.07 0.75
A1M 59 Target Target B2M 677 9 0.05 -0.91 0.15 0.77
ELC 355 Target Target DC-CK1 22 4 0.05 -0.90 0.18 0.77
CCL19 658 Target Target CCL5 2,002 52 0.05 -0.95 0.08 0.77
CCL7 274 Target Target CXCL9 1,016 24 0.05 -0.94 0.09 0.77
Erbb2 4,536 Target Target EGF 27,487 513 0.05 -0.93 0.11 0.72
CCL3 1,427 Target Target CXCL3 145 21 0.05 -0.92 0.14 0.76
Epigen 27 Target Target beta-Cellulin 17 1 0.05 -0.95 0.06 0.83
Carcinoma 433,099 Disease Target CEA 17,022 4,013 0.05 -0.87 0.24 0.65
CXCL9 1,016 Target Target CCL8 197 21 0.05 -0.94 0.11 0.77
EPHA3 140 Target Target EPHB2 385 11 0.05 -0.95 0.08 0.79
Exodus-2 27 Target Target CCL21 808 7 0.05 -0.86 0.26 0.76
Adenosine A3 Receptor 164 Target Target Adenosine A1 Receptor 1,432 23 0.05 -0.92 0.14 0.76
EPHA2 532 Target Target EPHA3 140 13 0.05 -0.94 0.09 0.78
CXCL16 341 Target Target CXCL10 2,386 43 0.05 -0.93 0.13 0.76
Draflazine 33 Drug Target Equilibrative Nucleoside Transporter 1 211 4 0.05 -0.93 0.12 0.79
EPHA4 357 Target Target EPHB3 118 10 0.05 -0.94 0.08 0.79
CAMK2A 42 Target Target ADRBK1 10 1 0.05 -0.94 0.10 0.81
Cathepsin G 1,613 Target Target Alpha-1 AntiChymotrypsin 1,460 75 0.05 -0.95 0.05 0.78
744.1 22 Target Target 464.1 19 1 0.05 -0.95 0.05 0.83
Platelet Aggregation 25,460 Disease Target Platelet Activating Factor 9,915 783 0.05 -0.94 0.08 0.73
CCL7 274 Target Target CXCL3 145 10 0.05 -0.95 0.07 0.80
EPHB4 329 Target Target EPHA2 532 21 0.05 -0.95 0.06 0.80
Ventricular Dysfunction 12,856 Disease Target BNP 6,842 477 0.05 -0.95 0.07 0.74
CD68 6,424 Target Target CD14 9,941 408 0.05 -0.95 0.06 0.75
CCL5 2,002 Target Target CCL1 220 34 0.05 -0.91 0.15 0.76
Thromboembolism 23,698 Disease Target Antithrombin 13,773 929 0.05 -0.95 0.07 0.73
CD22 1,591 Target Target CD72 198 29 0.05 -0.92 0.15 0.77
Angiotensin-Converting Enzyme 2 665 Target Target Renin 43,456 283 0.05 -0.76 0.43 0.70
CXCL11 526 Target Target CCL8 197 17 0.05 -0.94 0.09 0.79
CCL8 197 Target Target CCL1 220 11 0.05 -0.95 0.06 0.81
CCL2 3,560 Target Target CXCL3 145 38 0.05 -0.85 0.26 0.75
Phospholipase A2 13,400 Target Target Platelet Activating Factor 9,915 614 0.05 -0.95 0.06 0.75
CCL18 256 Target Target CCL14 34 5 0.05 -0.91 0.15 0.79
Leukemia 162,805 Disease Target CD34 24,598 3,403 0.05 -0.92 0.14 0.68
Carcinoma 433,099 Disease Target AFP 9,751 3,499 0.05 -0.80 0.36 0.66
Epidermal Growth Factor Receptor 24,772 Target Target ERBB3 1,154 289 0.05 -0.86 0.25 0.72
Diabetes 332,602 Disease Target Adiponectin 11,994 3,433 0.05 -0.84 0.29 0.66
CXCL7 76 Target Target CXCL2 750 13 0.05 -0.90 0.17 0.78
EPHB3 118 Target Target EPHA3 140 7 0.05 -0.95 0.06 0.82
CCL5 2,002 Target Target CXCL10/IP-10 114 27 0.06 -0.87 0.24 0.76
CXCL7 76 Target Target CCL8 197 7 0.06 -0.94 0.09 0.81
Epiregulin 291 Target Target EGF 27,487 162 0.06 -0.66 0.56 0.71
AMAC-1 19 Target Target CCL18 256 4 0.06 -0.88 0.21 0.79
CCL19 658 Target Target ELC 355 28 0.06 -0.94 0.08 0.80
CCL2 3,560 Target Target CXCL10/IP-10 114 37 0.06 -0.82 0.32 0.75
Acute Coronary Syndromes 9,133 Disease Target Bivalirudin 891 167 0.06 -0.89 0.19 0.74
CXCL7 76 Target Target CCL14 34 3 0.06 -0.94 0.09 0.82
CXCL3 145 Target Target CCL8 197 10 0.06 -0.94 0.07 0.82
CEA 17,022 Target Target AFP 9,751 765 0.06 -0.94 0.08 0.75
CCL5 2,002 Target Target CXCL2 750 73 0.06 -0.93 0.10 0.78
Beta-Glucosidase 4,297 Target Target Alpha-Glucosidase 4,319 261 0.06 -0.94 0.06 0.78
CEA 17,022 Target Target CA 72-4 184 108 0.06 -0.64 0.59 0.72
EPHB4 329 Target Target EPHB1 137 13 0.06 -0.93 0.09 0.81
CD14 9,941 Target Target CD34 24,598 970 0.06 -0.93 0.10 0.74
CXCL10 2,386 Target Target CXCL2 750 83 0.06 -0.93 0.11 0.78
CCL2 3,560 Target Target CCL1 220 55 0.06 -0.86 0.25 0.76
CCL7 274 Target Target CCL14 34 6 0.06 -0.90 0.18 0.80
CCL8 197 Target Target CXCL2 750 24 0.06 -0.92 0.12 0.79
CCL7 274 Target Target CXCL10 2,386 51 0.06 -0.89 0.19 0.77
EPHA4 357 Target Target EPHB1 137 14 0.06 -0.93 0.10 0.81
EGF 27,487 Target Target bFGF 9,327 1,029 0.06 -0.93 0.11 0.74
APOE 12,771 Target Target APOC1 126 82 0.06 -0.59 0.65 0.73
ACRP30 102 Target Target Adiponectin 11,994 72 0.07 -0.54 0.71 0.73
CCL4 5,638 Target Target CCL2 3,560 295 0.07 -0.93 0.08 0.78
EPHA4 357 Target Target EPHA2 532 29 0.07 -0.93 0.08 0.81
Kadsurenone 70 Drug Target Platelet Activating Factor 9,915 56 0.07 -0.45 0.80 0.73